Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.54 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459311 | 0.86 | MAPT (0.59) | MAPTALDH1A1KDM4ENPSR1NPC1 | |
| SCHEMBL6445038 | 0.86 | KMT2A (0.63) | MAPTALDH1A1KDM4EL3MBTL1NPSR1 | |
| SCHEMBL4453437 | 0.86 | KMT2A (0.63) | MAPTALDH1A1KDM4EL3MBTL1NPSR1 | |
| SCHEMBL4450066 | 0.80 | PRMT5 (0.50) | PRMT5WDR77MAPTALDH1A1KDM4E | |
| SCHEMBL4457837 | 0.80 | KDM4E (0.51) | MAPTALDH1A1KDM4ENPSR1NPC1 | |
| SCHEMBL4332906 | 0.79 | PRMT5 (0.49) | PRMT5WDR77MAPTALDH1A1KDM4E | |
| SCHEMBL4326738 | 0.76 | MAPT (0.78) | PRMT5WDR77MAPTALDH1A1KDM4E | |
| SCHEMBL4326742 | 0.76 | MAPT (0.78) | PRMT5WDR77MAPTALDH1A1KDM4E | |
| SCHEMBL4326934 | 0.75 | KDM4E (0.60) | MAPTALDH1A1KDM4EL3MBTL1NPSR1 | |
| SCHEMBL19215161 | 0.74 | PRMT5 (0.56) | PRMT5WDR77MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |