SCHEMBL4459668

SCHEMBL4459668

Clc1cc(Cl)c(-c2cc(Cl)cc(Cl)c2Cl)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
AHR P35869 7/20 0.55
TSHR P16473 4/20 0.48
HSD17B10 Q99714 4/20 0.48
HPGD P15428 3/20 0.48
SCN2A Q99250 1/20 0.42
CYP3A4 P08684 3/20 0.41
RECQL P46063 1/20 0.41
CES1 P23141 1/20 0.37
DNMT1 P26358 1/20 0.37
CNR2 P34972 1/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
CASP1 P29466 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2930780 0.88 ALDH1A1 (0.69) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4448731 0.87 ALDH1A1 (0.52) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4459067 0.86 ALDH1A1 (0.58) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4451811 0.86 ALDH1A1 (0.58) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4456396 0.85 ALDH1A1 (0.50) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4447150 0.83 ALDH1A1 (0.55) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL30621939 0.83 ALDH1A1 (0.55) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4450636 0.79 ALDH1A1 (0.50) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL29465223 0.79 ALDH1A1 (0.50) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4453636 0.78 ALDH1A1 (0.55) ALDH1A1AHRTSHRHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed