SCHEMBL4456396

SCHEMBL4456396

Clc1cc(Cl)c(Cl)c(-c2c(Cl)cccc2Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
AHR P35869 6/20 0.41
TSHR P16473 2/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GABRP O00591 2/20 0.38
GABRD O14764 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
GABRA2 P47869 2/20 0.38
GABRB2 P47870 2/20 0.38
GABRA4 P48169 2/20 0.38
GABRE P78334 2/20 0.38
GABRA6 Q16445 2/20 0.38
GABRG1 Q8N1C3 2/20 0.38
GABRG3 Q99928 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4459668 0.85 ALDH1A1 (0.61) ALDH1A1AHRTSHRHPGDHSD17B10
SCHEMBL4456505 0.84 ALDH1A1 (0.48) ALDH1A1AHRTSHRHPGDHSD17B10
SCHEMBL29465223 0.81 ALDH1A1 (0.50) ALDH1A1AHRTSHRHPGDHSD17B10
SCHEMBL30031148 0.81 AHR (0.50) ALDH1A1AHRTSHRHPGDHSD17B10
SCHEMBL4456481 0.81 ALDH1A1 (0.43) ALDH1A1AHRTSHRSCN2AHSP90AA1
SCHEMBL4450636 0.81 ALDH1A1 (0.50) ALDH1A1AHRTSHRHPGDHSD17B10
SCHEMBL4459297 0.81 AHR (0.50) ALDH1A1AHRTSHRHPGDHSD17B10
SCHEMBL29765253 0.79 ALDH1A1 (0.48) ALDH1A1AHRTSHRHPGDHSD17B10
SCHEMBL4453348 0.79 ALDH1A1 (0.48) ALDH1A1AHRTSHRHPGDHSD17B10
SCHEMBL2930780 0.79 ALDH1A1 (0.69) ALDH1A1AHRTSHRHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-118752281-A Magnetic coupling device with at least one sensor arrangement and demagnetizing capability 磁转换技术股份有限公司 2024-10-11 CN disclosed
CN-118367251-A Battery module with integrated pressure measurement 通用汽车环球科技运作有限责任公司 2024-07-19 CN disclosed
CN-115256001-B Magnetic coupling device with at least one sensor arrangement and demagnetizing capability 磁转换技术股份有限公司 2024-07-09 CN disclosed
CN-112004426-B Electronic cigarette with protective cover JT国际公司 2024-01-09 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-111508912-B Power covering structure and manufacturing method thereof 通用电气公司 2023-08-01 CN disclosed
CN-115882267-A Bicycle equipment provided with power supply unit 坎培诺洛有限公司 2023-03-31 CN disclosed
CN-115871830-A Bicycle equipment provided with power supply unit 坎培诺洛有限公司 2023-03-31 CN disclosed
CN-115871828-A Bicycle equipment provided with power supply unit 坎培诺洛有限公司 2023-03-31 CN disclosed
CN-115256001-A Magnetic coupling device with at least one sensor arrangement and degaussing capability 磁转换技术全球私人有限公司 2022-11-01 CN disclosed
CN-111093891-B Magnetic coupling device with at least one sensor arrangement and degaussing capability 磁转换技术全球私人有限公司 2022-08-02 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed