⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30535283 | 0.79 | LMNA (0.82) | — | |
| SCHEMBL676142 | 0.79 | LMNA (0.82) | — | |
| Potassium SCHEMBL6776357 | 0.77 | LMNA (0.78) | — | |
| SCHEMBL8179046 | 0.76 | LMNA (0.52) | — | |
| SCHEMBL8192284 | 0.75 | — | — | |
| SCHEMBL5016089 | 0.75 | — | — | |
| SCHEMBL16114401 | 0.75 | LMNA (0.75) | — | |
| SCHEMBL12539198 | 0.75 | — | — | |
| SCHEMBL14217552 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL8051614 | 0.75 | LMNA (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127301-A1 | 4-PHENYL-N-(PHENYL)THIAZOL-2-AMINE DERIVATIVES AND RELATED COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS FOR THE TREATMENT OF E.G. ANGIOGENESIS IMPLICATED OR INFLAMMATORY DISORDERS | Ikena Oncology, Inc. (US) | 2021-06-24 | — | — | WO | disclosed |
| CN-103814021-A | New dihydroquinoline-2-one derivatives | HOFFMANN LA ROCHE | 2014-05-21 | — | — | CN | disclosed |
| WO-2009144253-A1 | COMPOUNDS COMPRISING A 3-PYRIDINOL OR 5-PYRIMIDINOL RING HAVING AN ORGANOSELENO OR ORGANOTELLURO SUBSTITUENT FOR USE AS ANTIOXIDANTS | KAROLINSKA INSTITUTET INNOVATIONS AB (SE) | 2009-12-03 | — | — | WO | disclosed |