Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TEK | Q02763 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25295323 | 0.86 | MPO (0.48) | MPOLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL30509990 | 0.86 | MPO (0.48) | MPOLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL30509994 | 0.86 | MPO (0.48) | MPOLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL7494123 | 0.84 | RAB9A (0.68) | MPOLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL25252926 | 0.82 | MAPT (0.59) | MPOLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL18586550 | 0.81 | MPO (0.66) | MPOLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL29033970 | 0.80 | KDM4E (0.50) | MPOLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL30502863 | 0.80 | KDM4E (0.50) | MPOLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL25379052 | 0.79 | KDM4E (0.52) | MPOLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL30502865 | 0.79 | MPO (0.47) | MPOLMNAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |