Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435183 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2F2RL1POLB | |
| SCHEMBL524586 | 0.85 | KMT2A (0.64) | SMN1; SMN2KMT2AMEN1ATMALDH1A1 | |
| SCHEMBL13113227 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2KMT2AMEN1ATMANPEP | |
| SCHEMBL9544789 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2AMEN1ATMANPEP | |
| SCHEMBL7529531 | 0.83 | MEN1 (0.56) | KMT2AMEN1ATMANPEPERAP2 | |
| SCHEMBL8594413 | 0.83 | MEN1 (0.58) | SMN1; SMN2KMT2AMEN1ATMANPEP | |
| SCHEMBL13101471 | 0.81 | KMT2A (0.56) | SMN1; SMN2KMT2AMEN1ATMANPEP | |
| SCHEMBL1967746 | 0.81 | PKM (0.62) | SMN1; SMN2KMT2AATMALDH1A1CA12 | |
| SCHEMBL28661867 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AMEN1ATMANPEP | |
| SCHEMBL7924560 | 0.80 | SMN1; SMN2 (0.73) | SMN1; SMN2KMT2AMEN1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | CONSEJO SUPERIOR DE (ES) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | BAX, BCL2, CASP3 | SMN1; SMN2 1437/4885KMT2A 4770/4885MEN1 3458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.