SCHEMBL4459784

SCHEMBL4459784

Clc1ccc(Cl)c(-c2c(Cl)cc(Cl)c(Cl)c2Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.42
AHR P35869 7/20 0.42
CYP3A4 P08684 2/20 0.42
HTR2B P41595 1/20 0.41
PDE4D Q08499 1/20 0.41
ALDH1A1 P00352 5/20 0.40
CNR2 P34972 1/20 0.40
PTPN11 Q06124 1/20 0.39
IDO1 P14902 1/20 0.39
TSHR P16473 2/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453366 0.86 TP53 (0.46) TP53AHRCYP3A4HTR2BPDE4D
SCHEMBL4445059 0.84 TP53 (0.48) TP53AHRCYP3A4HTR2BPDE4D
SCHEMBL4456273 0.83 AHR (0.57) TP53AHRCYP3A4ALDH1A1TSHR
SCHEMBL4450570 0.82 TP53 (0.46) TP53AHRCYP3A4HTR2BPDE4D
SCHEMBL29618916 0.82 TP53 (0.46) TP53AHRCYP3A4HTR2BPDE4D
SCHEMBL29489601 0.81 TP53 (0.57) TP53AHRCYP3A4HTR2BPDE4D
SCHEMBL2852592 0.81 TP53 (0.57) TP53AHRCYP3A4HTR2BPDE4D
SCHEMBL4448731 0.79 ALDH1A1 (0.52) AHRCYP3A4ALDH1A1TSHRHSD17B10
SCHEMBL4454535 0.77 TP53 (0.52) TP53AHRCYP3A4HTR2BPDE4D
SCHEMBL4449569 0.77 AHR (0.58) AHRCYP3A4ALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-115803163-A Carding device with load sensing in neck 吉列有限责任公司 2023-03-14 CN disclosed
CN-216015541-U Energy storage module 上海派能能源科技股份有限公司 2022-03-11 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed