Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 7/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456266 | 1.00 | CTSS (0.45) | CTSSTDP1MAPTUSP2NPC1 | |
| SCHEMBL4455577 | 0.89 | CTSS (0.43) | CTSSMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4455581 | 0.89 | CTSS (0.43) | CTSSMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13409029 | 0.84 | CTSS (0.48) | CTSSTDP1MAPTUSP2NPC1 | |
| SCHEMBL4452899 | 0.82 | NPC1 (0.45) | CTSSTDP1MAPTNPC1RAB9A | |
| SCHEMBL4452895 | 0.82 | NPC1 (0.45) | CTSSTDP1MAPTNPC1RAB9A | |
| SCHEMBL4468902 | 0.82 | NPC1 (0.39) | CTSSTDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4459938 | 0.77 | ELANE (0.48) | CTSSTDP1MAPTUSP2NPC1 | |
| SCHEMBL4459935 | 0.77 | ELANE (0.48) | CTSSTDP1MAPTUSP2NPC1 | |
| SCHEMBL2543034 | 0.73 | NPC1 (0.54) | TDP1MAPTUSP2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |