Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 4/20 | 0.53 |
| ▸ | PKLR | P30613 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460822 | 0.90 | CNR1 (0.97) | CNR1KMT2AMEN1GAAPKM | |
| SCHEMBL4459981 | 0.88 | CNR1 (1.00) | CNR1KMT2AMEN1GAAPKM | |
| SCHEMBL4461762 | 0.88 | CNR1 (0.76) | CNR1KMT2AMEN1POLBGAA | |
| SCHEMBL4468884 | 0.86 | CNR1 (0.77) | CNR1POLBPKMPKLRTSHR | |
| SCHEMBL4467923 | 0.83 | CNR1 (0.68) | CNR1KMT2AMEN1POLBGAA | |
| SCHEMBL4463323 | 0.83 | CNR1 (0.68) | CNR1KMT2AMEN1POLBGAA | |
| SCHEMBL4466755 | 0.82 | CNR1 (0.86) | CNR1PKMPKLRTSHRLMNA | |
| SCHEMBL4462997 | 0.82 | CNR1 (0.78) | CNR1KMT2APOLBPKMPKLR | |
| SCHEMBL4460888 | 0.82 | CNR1 (0.71) | CNR1KMT2AMEN1PKMPKLR | |
| SCHEMBL4466220 | 0.81 | CNR1 (0.69) | CNR1KMT2AMEN1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534371-B2 | Liquid crystalline compound, liquid crystalline composition and retardation film | FUJIFILM CORPORATION (JP) | 2009-05-19 | — | — | US | claimed |
| US-20080169448-A1 | Liquid crystalline compound, liquid crystalline composition and retardation film | FUJIFILM CORPORATION (JP) | 2008-07-17 | — | — | US | claimed |
| US-7364670-B2 | Liquid crystalline compound, liquid crystalline composition and retardation film | FUJIFILM CORPORATION (JP) | 2008-04-29 | — | — | US | claimed |
| EP-1532132-B1 | NOVEL BENZODIOXOLES | HOFFMANN LA ROCHE (CH) | 2008-03-19 | — | — | EP | claimed |
| US-6900227-B2 | Benzodioxole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2005-05-31 | — | — | US | claimed |
| EP-1532132-A1 | NOVEL BENZODIOXOLES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-05-25 | — | — | EP | claimed |
| US-20050056811-A1 | Liquid crystalline compound, liquid crystalline composition and retardation film | FUJI PHOTO FILM CO., LTD. (JP) | 2005-03-17 | — | — | US | claimed |
| EP-1506991-A2 | Liquid crystalline compound, liquid crystalline composition and retardation film | FUJI PHOTO FILM CO., LTD. (JP) | 2005-02-16 | — | — | EP | claimed |
| US-20040142922-A1 | Benzodioxole derivatives | HOFFMANN-LA ROCHE INC. | 2004-07-22 | — | — | US | claimed |
| WO-2004013120-A1 | NOVEL BENZODIOXOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-12 | — | — | WO | claimed |
| US-7576088-B2 | Benzodioxole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-7576088-B2 | Benzodioxole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-7576088-B2 | Benzodioxole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-7534371-B2 | Liquid crystalline compound, liquid crystalline composition and retardation film | FUJIFILM CORPORATION (JP) | 2009-05-19 | — | — | US | disclosed |
| US-20080169448-A1 | Liquid crystalline compound, liquid crystalline composition and retardation film | FUJIFILM CORPORATION (JP) | 2008-07-17 | — | — | US | disclosed |
| US-6900227-B2 | Benzodioxole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2005-05-31 | — | — | US | disclosed |
| EP-1532132-A1 | NOVEL BENZODIOXOLES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-05-25 | — | — | EP | disclosed |
| US-20050056811-A1 | Liquid crystalline compound, liquid crystalline composition and retardation film | FUJI PHOTO FILM CO., LTD. (JP) | 2005-03-17 | — | — | US | disclosed |
| US-20040142922-A1 | Benzodioxole derivatives | HOFFMANN-LA ROCHE INC. | 2004-07-22 | — | — | US | disclosed |
| WO-2004013120-A1 | NOVEL BENZODIOXOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080169448-A1 | Liquid crystalline compound, liquid crystalline composition and retardation film | NCAPD2, RCC1, CCND2 | CNR1 2992/4885KMT2A 4169/4885MEN1 1851/4885 |
| US-20040142922-A1 | Benzodioxole derivatives | CNR1, CNR2, GPR119 | CNR1 1/4885KMT2A 3559/4885MEN1 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.