SCHEMBL446032

SCHEMBL446032

CCCCCC(C)(C)c1ccc(C(=O)OC(=O)c2ccc(C(C)(C)CCCCC)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 17/20 0.48
CNR1 P21554 7/20 0.47
HDAC3 O15379 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448815 0.83 RARB (0.50) CNR2MAPTALDH1A1
SCHEMBL8769760 0.82 CNR2 (0.49) CNR2CNR1HDAC3HDAC1HDAC2
SCHEMBL5486023 0.82 TP53 (0.53) CNR2CNR1MAPTALDH1A1
SCHEMBL448363 0.81 NPC1 (0.48) NPC1MAPTRAB9AALDH1A1
SCHEMBL22155358 0.81 CNR2 (0.55) CNR2CNR1HDAC3HDAC1HDAC2
SCHEMBL10529188 0.80 MAPT (0.62) CNR2CNR1NPC1MAPTRAB9A
SCHEMBL9301233 0.80 SRD5A2 (0.47) CNR2CNR1HDAC3HDAC1HDAC2
SCHEMBL6650215 0.78 CNR2 (0.49) CNR2CNR1ALDH1A1
SCHEMBL5196772 0.77 CNR2 (0.48) CNR2CNR1
SCHEMBL7825375 0.77 TP53 (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9290868-B2 Biodegradable nonwoven fabric and fiber product using the same JNC CORPORATION (JP) 2016-03-22 US disclosed
EP-2422005-B1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME JNC CORP (JP) 2013-12-04 EP disclosed
US-20120064789-A1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME JNC CORPORATION (JP) 2012-03-15 US disclosed
EP-2422005-A1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME JNC Corporation (JP) 2012-02-29 EP disclosed
WO-2010122806-A1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME CHISSO CORPORATION (JP) 2010-10-28 WO disclosed