Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 10/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650215 | 0.87 | CNR2 (0.49) | CNR2CNR1ALDH1A1 | |
| SCHEMBL448815 | 0.82 | RARB (0.50) | SRD5A2CNR2ALDH1A1 | |
| SCHEMBL8769760 | 0.81 | CNR2 (0.49) | CNR2HDAC3HDAC1HDAC2CNR1 | |
| SCHEMBL5486023 | 0.81 | TP53 (0.53) | SRD5A2CNR2CNR1ALDH1A1 | |
| Bicarbonate SCHEMBL10882220 | 0.80 | ESR1 (0.59) | CNR2ESR1ESR2CNR1ALDH1A1 | |
| SCHEMBL22155358 | 0.80 | CNR2 (0.55) | CNR2HDAC3HDAC1HDAC2CNR1 | |
| SCHEMBL446032 | 0.80 | CNR2 (0.48) | CNR2HDAC3HDAC1HDAC2CNR1 | |
| SCHEMBL24521549 | 0.79 | RAB9A (0.56) | ELANECNR2HDAC3 | |
| SCHEMBL199438 | 0.79 | CNR2 (0.49) | CNR2ESR1ESR2CNR1 | |
| SCHEMBL199439 | 0.79 | ESR1 (0.68) | CNR2ESR1ESR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356951-A | (Meth)acrylate monomer; composite filler; glass powder; fine particle filler; photoinitiator; surface smoothness; less shrinkage | GC CORPORATION (JP) | 1994-10-18 | — | — | US | disclosed |