⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952777 | 0.77 | TSHR (0.56) | — | |
| SCHEMBL8060600 | 0.77 | TSHR (0.56) | — | |
| SCHEMBL252121 | 0.77 | TSHR (0.56) | — | |
| SCHEMBL29987 | 0.74 | — | — | |
| SCHEMBL26091851 | 0.74 | SMN1; SMN2 (0.68) | — | |
| SCHEMBL6589055 | 0.74 | — | — | |
| SCHEMBL29988 | 0.74 | — | — | |
| SCHEMBL208522 | 0.74 | — | — | |
| SCHEMBL290484 | 0.72 | — | — | |
| SCHEMBL11963800 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773249-A | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2022-07-22 | — | — | CN | claimed |
| CN-114315827-A | Polycyclic pyridopyridazine amide oxime-containing carbocyclic derivatives and uses thereof | 维眸生物科技（上海）有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-113226324-A | Thiocarbamate derivatives as A2A inhibitors, pharmaceutical compositions thereof and combinations with anticancer agents | ITEOS比利时公司 | 2021-08-06 | — | — | CN | claimed |
| CN-113164462-A | Use of inhibitors of ENT family transporters in cancer therapy and combinations thereof with adenosine receptor antagonists | ITEOS比利时公司 | 2021-07-23 | — | — | CN | claimed |
| EP-3359154-B1 | WNT SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF | Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) | 2021-05-26 | — | — | EP | claimed |
| CN-107540664-B | Pyrazolyl pyrimidine ether compound and application thereof | 沈阳中化农药化工研发有限公司 | 2021-02-26 | — | — | CN | claimed |
| EP-3148587-B1 | CARBONITRILE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | PFIZER (US) | 2021-02-24 | — | — | EP | claimed |
| CN-108026088-B | Oxadiazole derivatives as HDAC inhibitors | 武田药品工业株式会社 | 2021-02-12 | — | — | CN | claimed |
| CN-112142621-A | Meta-diamide compound and preparation method and application thereof | 上海泰禾国际贸易有限公司 | 2020-12-29 | — | — | CN | claimed |
| US-20200347016-A1 | SUBSTITUTED PYRROLIDINES AS G-PROTEIN COUPLED RECEPTOR 43 AGONISTS | EPICS THERAPEUTICS (BE) | 2020-11-05 | — | — | US | claimed |
| EP-0022078-B1 | PYRAZOLO-QUINOLINES, PROCESSES FOR THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1984-07-25 | — | — | EP | claimed |
| EP-0075117-A2 | 2H-1,2,4,6-thiatriazine-1,1-dioxides, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1983-03-30 | — | — | EP | claimed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | claimed |
| US-4312870-A | TRANQUILIZERS, ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1982-01-26 | — | — | US | claimed |
| US-4263037-A | 5-Cyano-2,3-dihydrobenzofurans useful as herbicides | FISONS LIMITED (GB) | 1981-04-21 | — | — | US | claimed |
| US-4248788-A | INTERMEDIATES TO CINNAMOYLPIPERAZINES AND -HOMOPIPERAZINES | DELALANDE S.A. (FR) | 1981-02-03 | — | — | US | claimed |
| EP-0022078-A1 | Pyrazolo-quinolines, processes for their production, and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1981-01-07 | — | — | EP | claimed |
| US-4205169-A | N-[4-Azido-5-(2-ethoxyethyl)-6-phenyl-2-pyrimidinyl]acetamide and congeners | G. D. SEARLE & CO. (US) | 1980-05-27 | — | — | US | claimed |
| US-4178442-A | ANTIANGOROUS ACTIVITY | DELALANDE S. A. (FR) | 1979-12-11 | — | — | US | claimed |
| US-4052379-A | DYES FROM TRIFLUOROMETHYL-2-AMINOBENZOTHIAZOLE DIAZO COMPONENTS | EASTMAN KODAK COMPANY (US) | 1977-10-04 | — | — | US | claimed |