SCHEMBL4460740

SCHEMBL4460740

Fc1c(F)c(F)c(OCC[Zn])c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10458238 0.74 TSHR (0.30)
SCHEMBL9683149 0.74 LTA4H (0.39)
SCHEMBL13990834 0.72 TLR4 (0.32)
SCHEMBL5552756 0.72
SCHEMBL1930323 0.72 ALDH1A1 (0.37) POLBMAPTTDP1L3MBTL1
SCHEMBL23074670 0.72 TAAR1 (0.37)
SCHEMBL6474156 0.72
SCHEMBL9684782 0.70 NR5A1 (0.44)
SCHEMBL9685171 0.70 NR5A1 (0.44)
SCHEMBL12628260 0.70 KLK1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090069171-A1 Catalysts for olefin polymerization, process for production of the catalysts, and method for preservation thereof JAPAN POLYPROPYLENE CORPORATION (JP) 2009-03-12 US disclosed
EP-1881012-A1 CATALYSTS FOR OLEFIN POLYMERIZATION, PROCESS FOR PRODUCTION OF THE CATALYSTS, AND METHOD FOR PRESERVATION THEREOF Japan Polypropylene Corporation (JP) 2008-01-23 EP disclosed