Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 6/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 7/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454657 | 1.00 | EPHX1 (0.38) | EPHX1CES2THRBCTSLCTSB | |
| SCHEMBL4466652 | 1.00 | EPHX1 (0.38) | EPHX1CES2THRBCTSLCTSB | |
| SCHEMBL1119763 | 0.98 | — | — | |
| SCHEMBL2892756 | 0.91 | — | — | |
| SCHEMBL384256 | 0.88 | — | — | |
| SCHEMBL956731 | 0.80 | — | — | |
| SCHEMBL2058598 | 0.72 | SLC2A1 (0.38) | — | |
| SCHEMBL2018319 | 0.69 | — | — | |
| SCHEMBL7611194 | 0.69 | TSHR (0.42) | EPHX1CES2THRBCTSLCTSB | |
| SCHEMBL5586092 | 0.69 | TSHR (0.42) | EPHX1CES2THRBCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735438-B | Guanidino-containing catalysts | SIKA技术股份公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-107735438-A | Catalyst containing guanidine radicals | SIKA技术股份公司 | 2018-02-23 | — | — | CN | disclosed |
| EP-1524289-B1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-09-16 | — | — | EP | disclosed |
| US-20070149639-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | HORIKOSHI HIROSHI | 2007-06-28 | — | — | US | disclosed |
| EP-1524289-A1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-04-20 | — | — | EP | disclosed |
| US-20040254258-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| US-4656217-A | CURABLE CARBOXY-CONTAINING POLYMER MODIFIED BY AN UNSATURATED AZIRIDINE COMPOUND; ADHESIVES, CONCRETE SLABS; CASTINGS | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1987-04-07 | — | — | US | disclosed |