⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2892756 | 0.84 | — | — | |
| SCHEMBL1119763 | 0.82 | — | — | |
| SCHEMBL28923734 | 0.82 | — | — | |
| SCHEMBL454657 | 0.80 | EPHX1 (0.38) | — | |
| SCHEMBL4460742 | 0.80 | EPHX1 (0.38) | — | |
| SCHEMBL4466652 | 0.80 | EPHX1 (0.38) | — | |
| SCHEMBL4459168 | 0.77 | — | — | |
| SCHEMBL956909 | 0.77 | — | — | |
| SCHEMBL384256 | 0.74 | — | — | |
| SCHEMBL27399133 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735438-B | Guanidino-containing catalysts | SIKA技术股份公司 | 2020-06-09 | — | — | CN | disclosed |
| EP-3100723-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |
| US-9567338-B2 | Pyrazolo[3,4-d]pyrimidine compounds, their preparation and use as sigma ligands | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 2017-02-14 | — | — | US | disclosed |
| US-20170037018-A1 | Opsin-Binding Ligands, Compositions and Methods of Use | BIKAM PHARMACEUTICALS INC. (US) | 2017-02-09 | — | — | US | disclosed |
| US-9562022-B2 | Opsin-binding ligands, compositions and methods of use | BIKAM PHARMACEUTICALS, INC. (US) | 2017-02-07 | — | — | US | disclosed |
| EP-2734524-B1 | PYRAZOLO[3,4-d]PYRIMIDINE COMPOUNDS, THEIR PREPARATION AND USE AS SIGMA LIGANDS | ESTEVE LABOR DR (ES) | 2017-01-11 | — | — | EP | disclosed |
| EP-3100723-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | Bikam Pharmaceuticals, Inc. (US) | 2016-12-07 | — | — | EP | disclosed |
| EP-2230271-B1 | ADDITIVE FOR POLYMERIZABLE COMPOSITION, POLYMERIZABLE COMPOSITION CONTAINING THE SAME, AND USE OF THE POLYMERIZABLE COMPOSITION | MITSUI CHEMICALS INC (JP) | 2016-09-07 | — | — | EP | disclosed |
| EP-2442644-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2016-08-10 | — | — | EP | disclosed |
| EP-2982706-A1 | ADDITIVE FOR POLYMERIZABLE COMPOSITION, POLYMERIZABLE COMPOSITION CONTAINING THE SAME, AND USE OF THE POLYMERIZABLE COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2016-02-10 | — | — | EP | disclosed |
| EP-1233769-A4 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2004-12-29 | — | — | EP | disclosed |
| US-20040254258-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1484352-A1 | THIOEPOXY BASED POLYMERIZABLE COMPOSITION AND METHOD FOR PRODUCTION THEREOF | MITSUI CHEMICALS, INC. (JP) | 2004-12-08 | — | — | EP | disclosed |
| EP-1233769-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001037835-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC. (GB) | 2001-05-31 | — | — | WO | disclosed |
| US-5733882-A | Retroviral protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-31 | — | — | US | disclosed |
| EP-0602069-A4 | RETROVIRAL PROTEASE INHIBITORS. | SMITHKLINE BEECHAM CORP (US) | 1995-05-03 | — | — | EP | disclosed |
| EP-0602069-A1 | RETROVIRAL PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-22 | — | — | EP | disclosed |
| WO-1993002057-A1 | RETROVIRAL PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |
| US-4656217-A | CURABLE CARBOXY-CONTAINING POLYMER MODIFIED BY AN UNSATURATED AZIRIDINE COMPOUND; ADHESIVES, CONCRETE SLABS; CASTINGS | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1987-04-07 | — | — | US | disclosed |