SCHEMBL4460802

SCHEMBL4460802

CCCCCCCC(=O)SCCC[Si](OCCC)(OCCC)OCCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.40
CES2 O00748 3/20 0.37
CES1 P23141 3/20 0.37
ACHE P22303 2/20 0.37
GPR84 Q9NQS5 7/20 0.36
PPARG P37231 7/20 0.36
PPARD Q03181 7/20 0.36
PPARA Q07869 7/20 0.36
HDAC11 Q96DB2 5/20 0.36
TSHR P16473 4/20 0.36
PTPN1 P18031 3/20 0.36
ALDH1A1 P00352 2/20 0.36
TLR2 O60603 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
FABP4 P15090 2/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
SLC22A8 Q8TCC7 1/20 0.36
MEN1 O00255 1/20 0.36
ESR1 P03372 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29240691 0.98 DGKA (0.37) DGKACES2CES1ACHEGPR84
SCHEMBL29240797 0.92 DGKA (0.37) DGKACES2CES1ACHEGPR84
SCHEMBL29557281 0.89 CES2 (0.38) DGKACES2CES1GPR84PPARG
SCHEMBL21049760 0.89 CES2 (0.38) DGKACES2CES1GPR84PPARG
SCHEMBL30205683 0.89 CES2 (0.38) DGKACES2CES1GPR84PPARG
SCHEMBL4968748 0.89 CES2 (0.38) DGKACES2CES1GPR84PPARG
SCHEMBL96954 0.89 CES2 (0.38) DGKACES2CES1GPR84PPARG
SCHEMBL21049765 0.89 CES2 (0.38) DGKACES2CES1GPR84PPARG
SCHEMBL75725 0.89 CES2 (0.38) DGKACES2CES1GPR84PPARG
SCHEMBL6056905 0.89 CES2 (0.38) DGKACES2CES1GPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090143538-A1 Silane-Coupling-Agent-Treated Silica, Preparation Method Thereof, And Vibration-Damping And Vibration-Isolating Rubber Composition Containing The Same DOW CORNING TORAY CO., LTD. (JP) 2009-06-04 US claimed
US-20070244236-A1 Vibration-Damping And Vibration-Isolating Rubber Composition, Method Of Preparation Thereof, And Vibration-Damping And Vibration-Isolating Rubber Products DOW CORNING TORAY CO., LTD. (JP) 2007-10-18 US claimed
EP-1805254-A1 SILANE-COUPLING-AGENT-TREATED SILICA, PREPARATION METHOD THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION CONTAINING THE SAME Dow Corning Toray Co., Ltd. (JP) 2007-07-11 EP claimed
EP-1781734-A1 VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION, METHOD OF PREPARATION THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER PRODUCTS Dow Corning Toray Co., Ltd. (JP) 2007-05-09 EP claimed
WO-2006016699-A1 VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION, METHOD OF PREPARATION THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER PRODUCTS DOW CORNING TORAY CO., LTD. (JP) 2006-02-16 WO claimed
WO-2006016714-A1 SILANE-COUPLING-AGENT-TREATED SILICA, PREPARATION METHOD THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2006-02-16 WO claimed
CN-117924347-A Preparation method of monosulfur organosilane coupling agent 江西宏柏新材料股份有限公司 2024-04-26 CN disclosed
US-20090143538-A1 Silane-Coupling-Agent-Treated Silica, Preparation Method Thereof, And Vibration-Damping And Vibration-Isolating Rubber Composition Containing The Same DOW CORNING TORAY CO., LTD. (JP) 2009-06-04 US disclosed
US-20070244236-A1 Vibration-Damping And Vibration-Isolating Rubber Composition, Method Of Preparation Thereof, And Vibration-Damping And Vibration-Isolating Rubber Products DOW CORNING TORAY CO., LTD. (JP) 2007-10-18 US disclosed
EP-1805254-A1 SILANE-COUPLING-AGENT-TREATED SILICA, PREPARATION METHOD THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION CONTAINING THE SAME Dow Corning Toray Co., Ltd. (JP) 2007-07-11 EP disclosed
EP-1781734-A1 VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION, METHOD OF PREPARATION THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER PRODUCTS Dow Corning Toray Co., Ltd. (JP) 2007-05-09 EP disclosed
WO-2006016699-A1 VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION, METHOD OF PREPARATION THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER PRODUCTS DOW CORNING TORAY CO., LTD. (JP) 2006-02-16 WO disclosed
WO-2006016714-A1 SILANE-COUPLING-AGENT-TREATED SILICA, PREPARATION METHOD THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2006-02-16 WO disclosed