Biphenyl

Biphenyl

SCHEMBL4460858

POc1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
LTA4H P09960 1/20 0.45
TSHR P16473 1/20 0.45
CA4 P22748 1/20 0.41
MAPK1 P28482 2/20 0.39
TAAR1 Q96RJ0 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NOTUM Q6P988 1/20 0.39
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
RECQL P46063 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
KCNA3 P22001 1/20 0.38
AKT1 P31749 1/20 0.37
AKT2 P31751 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26509944 0.92 ALDH1A1 (0.50) ALDH1A1LTA4HMAPK1TAAR1CYP1A2
SCHEMBL15382357 0.92 ALDH1A1 (0.50) ALDH1A1LTA4HMAPK1TAAR1CYP1A2
SCHEMBL66653 0.91
Potassium SCHEMBL29460314 0.88
SCHEMBL29460272 0.88
Water SCHEMBL27849179 0.88
Hydrochloric Acid SCHEMBL27878361 0.88
Hydrochloric Acid SCHEMBL28484728 0.88 LTA4H (0.50) ALDH1A1LTA4HTSHRCA4TAAR1
Lithium SCHEMBL29460305 0.88
SCHEMBL27075439 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104271607-B Hydrogenation of nitrile rubbers 阿朗新科德国有限责任公司 2017-05-24 CN disclosed
CN-103974772-B Including ruthenium or the carbon monoxide-olefin polymeric and its purposes for hydrogenated nitrile-butadiene rubber of osmium carbene complex and terminal olefin 阿朗新科德国有限责任公司 2017-03-29 CN disclosed
CN-103890012-B Catalyst compositions and their use for hydrogenating nitrile rubbers 朗盛德国有限责任公司 2016-12-14 CN disclosed
CN-104023845-B Including croup Si-lotus Victor type complex compound and the carbon monoxide-olefin polymeric of terminal olefin and the purposes for hydrogenated nitrile-butadiene rubber thereof 朗盛德国有限责任公司 2016-10-05 CN disclosed
CN-103857688-B Complex catalyst based on ruthenium 多伦多大学管理委员会 2016-08-17 CN disclosed
CN-104024279-B Carbon monoxide-olefin polymeric and for the purposes of hydrogenated nitrile-butadiene rubber LANXESS DEUTSCHLAND GMBH (DE) 2016-05-04 CN disclosed
CN-104271607-A Hydrogenation of nitrile rubbers LANXESS DEUTSCHLAND GMBH 2015-01-07 CN disclosed
CN-104023845-A CATALYST COMPOSITIONS COMPRISING A GRUBBS-HOVEYDA TYPE COMPLEX AND A TERMINAL OLEFIN AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER LANXESS DEUTSCHLAND GMBH 2014-09-03 CN disclosed
CN-104024279-A Catalyst Compositions And Their Use For Hydrogenation Of Nitrile Rubber LANXESS DEUTSCHLAND GMBH 2014-09-03 CN disclosed
CN-103974772-A Catalyst compositions and their use for hydrogenation of nitrile rubber LANXESS DEUTSCHLAND GMBH 2014-08-06 CN disclosed
CN-101052665-A Novel copolyester compositions with improved impact strength at low temperatures EASTMAN CHEM CO (US) 2007-10-10 CN disclosed
CN-101048462-A Neopentyl glycol containing polyesters blended with polycarbonates EASTMAN CHEM CO (US) 2007-10-03 CN disclosed
CN-1331843-C Preparation of dinitrile compound RHODIA POLYAMIDE INTERMEDIATES (FR) 2007-08-15 CN disclosed
CN-1898324-A Polymer blends with improved rheology and improved unnotched impact strength EASTMAN CHEM CO (US) 2007-01-17 CN disclosed
CN-1898326-A Compatibilized blends of biodegradable polymers with improved rheology EASTMAN CHEM CO (US) 2007-01-17 CN disclosed
CN-1288122-C Process for producing carbonyl compound NAT INST OF ADVANCED IND SCIEN (JP) 2006-12-06 CN disclosed
CN-1747927-A Process for producing dinitrile compound RHODIA POLYAMIDE INTERMEDIATES (FR) 2006-03-15 CN disclosed
CN-1639099-A Process for producing carbonyl compound NAT INST OF ADVANCED IND SCIEN (JP) 2005-07-13 CN disclosed
US-4391761-A Process for the production of aryl phosphonyl compounds BAYER AKTIENGESELLSCHAFT (DE) 1983-07-05 US disclosed
US-4377537-A FROM TRIARYL PHOSPHITE AND ALKYL PHOSPHITE OR PHOSPHONOUS ACID DIARYL ESTER AND PHOSPHONOUS ACID DIALKYL ESTER BAYER AKTIENGESELLSCHAFT (DE) 1983-03-22 US disclosed