Thymidine_Triphosphate

Thymidine_Triphosphate

SCHEMBL4461391

Cc1cn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 12/20 0.73
P2RY2 P41231 9/20 0.73
P2RY4 P51582 3/20 0.64
POLB P06746 1/20 0.62
POLA1 P09884 1/20 0.62
POLD1 P28340 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thymidine_Triphosphate SCHEMBL18852394 1.00 P2RY6 (0.73) P2RY6P2RY2P2RY4POLBPOLA1
Thymidine_Triphosphate SCHEMBL3502894 1.00 P2RY6 (0.73) P2RY6P2RY2P2RY4POLBPOLA1
Thymidine_Triphosphate SCHEMBL17210989 1.00 P2RY6 (0.73) P2RY6P2RY2P2RY4POLBPOLA1
Thymidine_Triphosphate SCHEMBL17211051 1.00 P2RY6 (0.73) P2RY6P2RY2P2RY4POLBPOLA1
Thymidine_Triphosphate SCHEMBL625179 1.00 P2RY6 (0.73) P2RY6P2RY2P2RY4POLBPOLA1
SCHEMBL3019703 0.98 P2RY6 (0.70) P2RY6P2RY2P2RY4
SCHEMBL3019709 0.98 P2RY6 (0.70) P2RY6P2RY2P2RY4
SCHEMBL17364583 0.98 P2RY6 (0.70) P2RY6P2RY2P2RY4
SCHEMBL8156931 0.94 P2RY6 (0.66) P2RY6P2RY2P2RY4
SCHEMBL21577343 0.92 P2RY6 (0.63) P2RY6P2RY2P2RY4POLBPOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1594987-B1 NUCLEIC ACID SEQUENCING METHODS, KITS AND REAGENTS GENEFORM TECHNOLOGIES LTD (GB) 2009-05-27 EP claimed
US-20210340612-A1 PROCESS FOR COGNATE NUCLEOTIDE DETECTION IN A NUCLEIC ACID SEQUENCING WORKFLOW Omniome, Inc. (US) 2021-11-04 US disclosed
US-10975427-B2 Process for cognate nucleotide detection in a nucleic acid sequencing workflow Omniome, Inc. (US) 2021-04-13 US disclosed
US-20180208983-A1 PROCESS FOR COGNATE NUCLEOTIDE DETECTION IN A NUCLEIC ACID SEQUENCING WORKFLOW Omniome, Inc. (US) 2018-07-26 US disclosed
US-8399196-B2 Nucleic acid sequencing methods, kits and reagents GENEFORM TECHNOLOGIES LIMITED (GB) 2013-03-19 US disclosed
EP-1594987-B1 NUCLEIC ACID SEQUENCING METHODS, KITS AND REAGENTS GENEFORM TECHNOLOGIES LTD (GB) 2009-05-27 EP disclosed
US-20070148645-A1 Nucleic acid sequencing methods, kits and reagents GENEFORM TECHNOLOGIES LIMITED (GB) 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180208983-A1 PROCESS FOR COGNATE NUCLEOTIDE DETECTION IN A NUCLEIC ACID SEQUENCING WORKFLOW RNGTT, POLRMT, POLM P2RY6 706/4885P2RY2 1576/4885P2RY4 625/4885
US-20070148645-A1 Nucleic acid sequencing methods, kits and reagents UNG, DNTT, RNGTT P2RY6 1915/4885P2RY2 3016/4885P2RY4 2195/4885
US-10975427-B2 Process for cognate nucleotide detection in a nucleic acid sequencing workflow RNGTT, POLRMT, POLM P2RY6 706/4885P2RY2 1576/4885P2RY4 625/4885
US-20210340612-A1 PROCESS FOR COGNATE NUCLEOTIDE DETECTION IN A NUCLEIC ACID SEQUENCING WORKFLOW RNGTT, POLRMT, POLM P2RY6 706/4885P2RY2 1576/4885P2RY4 625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.