SCHEMBL4461499

SCHEMBL4461499

O=C(O)NC1CC2CCC1C2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.59
EPHX1 P07099 1/20 0.58
SIGMAR1 Q99720 4/20 0.54
TAS1R3 Q7RTX0 1/20 0.54
TAS1R1 Q7RTX1 1/20 0.54
TAS1R2 Q8TE23 1/20 0.54
HPGD P15428 3/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ALDH1A1 P00352 3/20 0.50
GRIN2D O15399 2/20 0.49
GRIN3B O60391 2/20 0.49
GRIN1 Q05586 2/20 0.49
GRIN2A Q12879 2/20 0.49
GRIN2B Q13224 2/20 0.49
GRIN2C Q14957 2/20 0.49
GRIN3A Q8TCU5 2/20 0.49
MAPT P10636 1/20 0.49
HSD17B10 Q99714 2/20 0.46
POLB P06746 1/20 0.46
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15655473 1.00 EPHX2 (0.59) EPHX2EPHX1SIGMAR1TAS1R3TAS1R1
SCHEMBL15655475 1.00 EPHX2 (0.59) EPHX2EPHX1SIGMAR1TAS1R3TAS1R1
SCHEMBL26089624 1.00 EPHX2 (0.59) EPHX2EPHX1SIGMAR1TAS1R3TAS1R1
SCHEMBL15655476 1.00 EPHX2 (0.59) EPHX2EPHX1SIGMAR1TAS1R3TAS1R1
SCHEMBL3068813 0.84 EPHX1 (0.76) EPHX2EPHX1SIGMAR1TAS1R3TAS1R1
SCHEMBL3071717 0.84 EPHX2 (0.61) EPHX2EPHX1SIGMAR1TAS1R3TAS1R1
SCHEMBL23573482 0.83 EPHX1 (0.54) EPHX2EPHX1SIGMAR1TAS1R3TAS1R1
SCHEMBL7610644 0.81 EPHX2 (0.58) EPHX2EPHX1SIGMAR1TAS1R3TAS1R1
SCHEMBL5590888 0.81 EPHX2 (0.58) EPHX2EPHX1SIGMAR1TAS1R3TAS1R1
SCHEMBL19688352 0.81 EPHX2 (0.58) EPHX2EPHX1SIGMAR1TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708320-B2 Environmentally-friendly hydroazidation of olefins GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-07-25 US disclosed
WO-2023069708-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF MONTE ROSA THERAPEUTICS, INC. (US) 2023-04-27 WO disclosed
US-20210284601-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-09-16 US disclosed
EP-2968211-B1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME BIO PHARM SOLUTIONS CO LTD (KR) 2021-05-12 EP disclosed
EP-3784660-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS Georgia State University Research Foundation, Inc. (US) 2021-03-03 EP disclosed
EP-2797878-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO-PHARM SOLUTIONS CO LTD (KR) 2017-08-16 EP disclosed
US-7622526-B2 Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material ESSILOR INTERNATIONAL (FR) 2009-11-24 US disclosed
US-20060270771-A1 Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2006-11-30 US disclosed
CN-1268679-A Chemical enhancement type photoetching gum NEC CORP (JP) 2000-10-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708320-B2 Environmentally-friendly hydroazidation of olefins HAO2, AHR, HMOX1 EPHX2 876/4885EPHX1 314/4885SIGMAR1 1512/4885
US-20210284601-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS HAO2, AHR, HMOX1 EPHX2 876/4885EPHX1 314/4885SIGMAR1 1512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.