Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | MMP8 | P22894 | 3/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4325084 | 0.93 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4331742 | 0.89 | CA2 (0.37) | SLC6A4SLC6A2SLC6A3HRH3CA2 | |
| SCHEMBL4326421 | 0.88 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3MMP8MMP3 | |
| SCHEMBL4462120 | 0.77 | CA2 (0.38) | SLC6A4SLC6A2SLC6A3HRH3CA2 | |
| SCHEMBL4336739 | 0.77 | KMT2A (0.33) | SLC6A4SLC6A2SLC6A3KMT2AMEN1 | |
| SCHEMBL4321880 | 0.76 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3KMT2AHRH3 | |
| SCHEMBL4323128 | 0.73 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4336742 | 0.72 | KMT2A (0.31) | SLC6A4KMT2AMEN1HRH3 | |
| SCHEMBL4316957 | 0.71 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4338664 | 0.70 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |