Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461859 | 0.89 | SLC6A4 (0.39) | CA2SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4462120 | 0.88 | CA2 (0.38) | CA2SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4336739 | 0.85 | KMT2A (0.33) | SLC6A4HRH3SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL4325084 | 0.82 | SLC6A4 (0.43) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4321880 | 0.75 | SLC6A4 (0.42) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4459918 | 0.69 | SLC6A4 (0.44) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4316512 | 0.67 | SLC6A4 (0.52) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4323128 | 0.66 | SLC6A4 (0.55) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4322610 | 0.65 | KMT2A (0.42) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4326089 | 0.65 | SLC6A4 (0.45) | SLC6A4HRH3SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |