SCHEMBL4461899

SCHEMBL4461899

CC(OP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@H]1O[C@@H](n2ccc(N)nc2=O)C[C@@H]1O

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLG P54098 3/20 0.61
POLB P06746 1/20 0.54
P2RY2 P41231 9/20 0.49
P2RY4 P51582 5/20 0.49
P2RY6 Q15077 3/20 0.49
CACNA1F O60840 2/20 0.39
LMNA P02545 2/20 0.39
ALB P02768 2/20 0.39
MAPT P10636 2/20 0.39
CACNA1D Q01668 2/20 0.39
CACNA1S Q13698 2/20 0.39
CACNA1C Q13936 2/20 0.39
PDE3A Q14432 2/20 0.39
NT5E P21589 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6914072 0.90 POLG (0.62) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL585723 0.89 POLG (0.60) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL1274297 0.89 POLG (0.72) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL17215882 0.89 POLG (0.61) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL4419522 0.88 POLG (0.61) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL30166144 0.87 POLG (0.57) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL10900394 0.84 POLG (0.56) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL1274372 0.84 POLG (0.55) POLGP2RY2P2RY4P2RY6LMNA
SCHEMBL13173263 0.84 POLG (0.55) POLGP2RY2P2RY4P2RY6LMNA
SCHEMBL800406 0.84 POLG (0.55) POLGP2RY2P2RY4P2RY6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240002920-A1 METHOD AND KIT FOR DETECTING DNA METHYLATION BASED ON QUANTITATIVE POLYMERASE CHAIN REACTION (qPCR) ZHU YUNFENG (CN) 2024-01-04 US claimed
US-20240002920-A1 METHOD AND KIT FOR DETECTING DNA METHYLATION BASED ON QUANTITATIVE POLYMERASE CHAIN REACTION (qPCR) ZHU YUNFENG (CN) 2024-01-04 US disclosed
CN-116917266-A Ionizable lipids and methods of making and using the same 乔治梅森研究基金会公司 2023-10-20 CN disclosed
US-8772006-B2 Compositions and methods utilizing DNA polymerases AGILENT TECHNOLOGIES, INC. (US) 2014-07-08 US disclosed
US-8268605-B2 Thermococcus mutant genetic engineering; heat resistance AGILENT TECHNOLOGIES, INC. (US) 2012-09-18 US disclosed
EP-1766065-A4 COMPOSITIONS AND METHODS FOR SYNTHESIZING cDNA STRATAGENE CALIFORNIA (US) 2009-08-05 EP disclosed
US-20080280291-A1 Compositions and methods utilizing DNA polymerases AGILENT TECHNOLOGIES, INC. 2008-11-13 US disclosed
EP-1766065-A2 COMPOSITIONS AND METHODS FOR SYNTHESIZING cDNA Stratagene California (US) 2007-03-28 EP disclosed
EP-1226255-B1 COMPOSITIONS AND METHODS UTILIZING DNA POLYMERASES STRATAGENE CALIFORNIA (US) 2006-03-29 EP disclosed
WO-2005118866-A2 COMPOSITIONS AND METHODS FOR SYNTHESIZING cDNA STRATAGENE CALIFORNIA (US) 2005-12-15 WO disclosed
US-6946273-B1 Compositions and methods utilizing DNA polymerases STRATAGENE CALIFORNIA (US) 2005-09-20 US disclosed
US-20050158730-A1 Compositions and methods utilizing DNA polymerases STRATAGENE CALIFORNIA 2005-07-21 US disclosed
US-20050123940-A1 Compositions and methods for synthesizing cDNA STRATAGENE CALIFORNIA 2005-06-09 US disclosed
EP-1412491-A4 COMPOSITIONS AND METHODS UTILIZING DNA POLYMERASES STRATAGENE CALIFORNIA (US) 2005-02-02 EP disclosed
EP-1412491-A2 COMPOSITIONS AND METHODS UTILIZING DNA POLYMERASES Stratagene California (US) 2004-04-28 EP disclosed
US-20040009486-A1 Compositions and methods utilizing DNA polymerases STRATAGENE CALIFORNIA 2004-01-15 US disclosed
US-20030157483-A1 Compositions and methods utilizing DNA polymerases AGILENT TECHNOLOGIES, INC. 2003-08-21 US disclosed
WO-2003054139-A2 COMPOSITIONS AND METHODS UTILIZING DNA POLYMERASES STRATAGENE (US) 2003-07-03 WO disclosed