Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.50 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.50 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461899 | 0.90 | POLG (0.61) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL17215882 | 0.90 | POLG (0.61) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL1274297 | 0.90 | POLG (0.72) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL4419522 | 0.89 | POLG (0.61) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL585723 | 0.88 | POLG (0.60) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL30166144 | 0.86 | POLG (0.57) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL10900394 | 0.85 | POLG (0.56) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL5086151 | 0.84 | POLG (0.56) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL6672414 | 0.83 | POLG (0.56) | POLGP2RY2P2RY4P2RY6LMNA | |
| SCHEMBL9389237 | 0.83 | POLG (0.55) | POLGPOLBP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084266-B1 | THE APPLICATION OF 5'-MODIFIED NUCLEOTIDES IN MOLECULAR BIOLOGY AND MEDICINE | EUROP LAB MOLEKULARBIOLOG (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-6627416-B1 | Synthesizing copies of double-stranded nucleic acid from a single-stranded one by enzymatic incorporation of compound of given formula; site-directed cleavage; use for detecting nucleic acids and mutations and for sequencing | EUROPAISCHES LABORATORIUM FUR MOLEKULARBIOLOGIE (EMBL) (DE) | 2003-09-30 | — | — | US | disclosed |
| EP-1084266-A2 | 5'-MODIFIED NUCLEOTIDES AND THE APPLICATION THEREOF IN MOLECULAR BIOLOGY AND MEDICINE | Europäisches Laboratorium für Molekularbiologie (DE) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999053087-A2 | 5'-MODIFIED NUCLEOTIDES AND THE APPLICATION THEREOF IN MOLECULAR BIOLOGY AND MEDICINE | Europäisches Laboratorium für Molekularbiologie (EMBL) (DE) | 1999-10-21 | — | — | WO | disclosed |