Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.48 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.48 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419522 | 0.89 | POLG (0.61) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL9389237 | 0.88 | POLG (0.55) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL585723 | 0.88 | POLG (0.60) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL7520065 | 0.88 | POLG (0.54) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL6914072 | 0.85 | POLG (0.62) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL10903456 | 0.84 | NT5E (0.55) | POLGP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL17215882 | 0.84 | POLG (0.61) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL1274297 | 0.84 | POLG (0.72) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL4461899 | 0.84 | POLG (0.61) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL5086151 | 0.81 | POLG (0.56) | POLGPOLBP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4587044-A | Linkage of proteins to nucleic acids | THE JOHNS HOPKINS UNIVERSITY (US) | 1986-05-06 | — | — | US | disclosed |