SCHEMBL9237295

SCHEMBL9237295

CCOP(=O)(OCC)C(O)P(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.46
POLB P06746 1/20 0.46
TSHR P16473 2/20 0.42
GAA P10253 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
LAP3 P28838 1/20 0.36
FDPS P14324 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10859409 0.79 TSHR (0.40) PPARDPOLBTSHRGAATP53
Ammonia Solution, Strong SCHEMBL10858881 0.79 TSHR (0.40) PPARDPOLBTSHRGAATP53
SCHEMBL9162193 0.78 TSHR (0.43) PPARDPOLBTSHRGAAL3MBTL1
SCHEMBL8549163 0.78 TSHR (0.43) PPARDPOLBTSHRGAAL3MBTL1
SCHEMBL3904945 0.77 POLB (0.50) PPARDPOLBTSHRGAAL3MBTL1
SCHEMBL4462235 0.77 POLB (0.50) PPARDPOLBTSHRGAAL3MBTL1
SCHEMBL27268583 0.76 TSHR (0.42) PPARDPOLBTSHRGAAL3MBTL1
SCHEMBL10861877 0.76 PPARD (0.38) PPARDPOLBTSHRL3MBTL1TP53
SCHEMBL3822346 0.75 POLB (0.48) PPARDPOLBTSHRGAAL3MBTL1
SCHEMBL3405218 0.74 LAP3 (0.44) PPARDPOLBTSHRTP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0638577-A1 Process for the preparation of N-substituted aminoalkylenephosphonic acid esters HOECHST AKTIENGESELLSCHAFT (DE) 1995-02-15 EP disclosed
US-4254018-A DISCOLORATION INHIBITION DURING POLYMERIZATION AKZONA INCORPORATED (US) 1981-03-03 US disclosed