SCHEMBL4462284

SCHEMBL4462284

COc1ccc(CC(OC)C(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.71
PPARA Q07869 18/20 0.69
PPARG P37231 17/20 0.69
PPARD Q03181 5/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4462278 1.00 LDHA (0.71) LDHAPPARAPPARGPPARD
SCHEMBL27654978 0.86 PPARA (0.76) LDHAPPARAPPARGPPARD
SCHEMBL5383887 0.85 PPARA (0.84) LDHAPPARAPPARGPPARD
SCHEMBL27674846 0.85 PPARA (0.84) LDHAPPARAPPARGPPARD
SCHEMBL6055973 0.85 PPARA (0.73) LDHAPPARAPPARGPPARD
SCHEMBL5383883 0.85 PPARA (0.84) LDHAPPARAPPARGPPARD
SCHEMBL4455247 0.85 PPARA (0.73) LDHAPPARAPPARGPPARD
SCHEMBL4405215 0.84 LDHA (0.59) LDHAPPARAPPARGPPARD
SCHEMBL4455242 0.84 LDHA (0.59) LDHAPPARAPPARGPPARD
SCHEMBL3466702 0.84 PPARA (0.56) LDHAPPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4346810-A1 COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF Unigen, Inc. (US) 2024-04-10 EP disclosed
CN-117794534-A Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof 尤尼根公司 2024-03-29 CN disclosed
WO-2022256624-A1 COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF UNIGEN, INC. (US) 2022-12-08 WO disclosed
US-20090029429-A1 Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative KANEKA CORPORATION (JP) 2009-01-29 US disclosed
EP-1801224-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-SUBSTITUENT-OXY-3-(4-SUBSTITUENT-OXYPHENYL)­PROPIONIC ACID DERIVATIVE Kaneka Corporation (JP) 2007-06-27 EP disclosed