Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14285179 | 0.85 | ACACB (0.53) | PPARGPPARAACACBPPARD | |
| SCHEMBL14285167 | 0.85 | ACACB (0.53) | PPARGPPARAACACBPPARD | |
| SCHEMBL542970 | 0.84 | ESR1 (0.63) | — | |
| SCHEMBL5024580 | 0.84 | ESR1 (0.63) | — | |
| SCHEMBL4462278 | 0.84 | LDHA (0.71) | LDHAPPARGPPARAPPARD | |
| SCHEMBL542969 | 0.84 | ESR1 (0.63) | — | |
| SCHEMBL4462284 | 0.84 | LDHA (0.71) | LDHAPPARGPPARAPPARD | |
| SCHEMBL4460117 | 0.84 | ACACB (0.50) | LDHAPPARGPPARAACACBPPARD | |
| SCHEMBL14285180 | 0.83 | PPARA (0.51) | PPARGPPARAPPARDALDH1A1 | |
| SCHEMBL14366413 | 0.83 | PPARG (0.58) | PPARGPPARAACACBPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |