SCHEMBL4462319

SCHEMBL4462319

CC(CCC(OOC(=O)c1ccccc1)C(C)C)OOC(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
F2 P00734 1/20 0.47
TSHR P16473 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HSD17B10 Q99714 1/20 0.42
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
POLB P06746 1/20 0.38
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
TP53 P04637 1/20 0.38
NPC1 O15118 1/20 0.37
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8166783 1.00 LMNA (0.47) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL10340068 0.91 LMNA (0.57) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL5665671 0.88 TSHR (0.49) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL6561805 0.86 LMNA (0.52) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL9860726 0.84 TDP1 (0.54) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL5055172 0.81 LMNA (0.46) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL27519361 0.80 ALDH1A1 (0.49) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL8467742 0.79 LMNA (0.55) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL10108072 0.76 ALDH1A1 (0.59) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL245415 0.75 LMNA (0.64) LMNAF2TSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006023371-A1 FUNCTIONALIZED POLY(ARYLENE ETHER) COMPOSITION AND METHOD GENERAL ELECTRIC COMPANY (US) 2006-03-02 WO claimed
US-5545679-A CURRENT LIMITERS, RESETTABLE FUSES EATON CORPORATION (US) 1996-08-13 US claimed
US-11149162-B2 Aqueous dispersion, coating film, and laminate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-10-19 US disclosed
US-11072696-B2 Nitrile group-containing copolymer rubber and nitrile group-containing copolymer rubber cross-linked product ZEON CORPORATION (JP) 2021-07-27 US disclosed
WO-2019188089-A1 THERMOSETTING RESIN COMPOSITION 株式会社大阪ソーダ 2019-10-03 WO disclosed
US-20190177568-A1 AQUEOUS DISPERSION, COATING FILM, AND LAMINATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-06-13 US disclosed
CN-106574012-B 2,3,3,3- tetrafluoro-1-propene is used for the preparation of butyl rubber as diluent 阿朗新科新加坡私人有限公司 2019-04-19 CN disclosed
CN-109563212-A Thermohardening type composition 东亚合成株式会社 2019-04-02 CN disclosed
EP-3456780-A1 AQUEOUS DISPERSION, COATING FILM, AND LAMINATE Sumitomo Chemical Company Limited (JP) 2019-03-20 EP disclosed
CN-108699343-A Curable composition for producing resin sheet providing tough cured product 东亚合成株式会社 2018-10-23 CN disclosed
CN-107207643-A Resin sheet manufacture curing composition 东亚合成株式会社 2017-09-26 CN disclosed
EP-0404303-A1 Glass fiber-reinforced resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-12-27 EP disclosed
EP-0386780-A2 Photosensitive composition NIPPON PAINT CO., LTD. (JP) 1990-09-12 EP disclosed
EP-0368345-A2 Thermoplastic olefin resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-05-16 EP disclosed
EP-0362827-A1 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-11 EP disclosed
EP-0356194-A2 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-02-28 EP disclosed
EP-0328364-A2 Photosensitive material CANON KABUSHIKI KAISHA (JP) 1989-08-16 EP disclosed
EP-0321264-A2 Multilayer polymeric composite, method for its manufacture, and lightweight durable articles fabricated therefrom AMERICAN STANDARD INC. (US) 1989-06-21 EP disclosed
EP-0315988-A2 Photopolymerizable composition Nippon Paint Co., Ltd. (JP) 1989-05-17 EP disclosed
US-4187260-A BIS(TERT-BUTYLPEROXY)DIMETHYLHEXYNE, ALKENYLAROMATIC, DIENE RUBBER MONSANTO COMPANY (US) 1980-02-05 US disclosed