Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459771 | 0.66 | GRM2 (0.40) | GRM2BACE1 | |
| SCHEMBL4463022 | 0.63 | MDM2 (0.39) | ALDH1A1TNKSKDM4EHPGDHSD17B10 | |
| SCHEMBL4463013 | 0.61 | TNKS (0.41) | ALDH1A1TNKSKDM4ECYP3A4CYP1A2 | |
| SCHEMBL9105021 | 0.59 | PKM (0.37) | ALDH1A1GAATSHRKMT2ANPSR1 | |
| SCHEMBL28994076 | 0.58 | ALDH1A1 (0.39) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL8357258 | 0.58 | CYP2A6 (0.62) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL15744020 | 0.57 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL15744004 | 0.57 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL22771076 | 0.57 | HCAR2 (0.39) | GRM2TNKSBACE1KDM4EHSD17B10 | |
| SCHEMBL22771265 | 0.57 | HCAR2 (0.37) | TNKSBACE1KDM4EHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137577-A1 | HETEROCYCLIC COMPOUNDS | PFIZER INC. | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137577-A1 | HETEROCYCLIC COMPOUNDS | CYP2D6, ABCG2, CYP2B6 | ALDH1A1 150/4885GAA 121/4885GRM2 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.