Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760631 | 0.80 | MEN1 (0.47) | NPSR1L3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL4336942 | 0.79 | SIGMAR1 (0.53) | NPSR1L3MBTL1ALDH1A1CES1MAOA | |
| SCHEMBL9171286 | 0.79 | NPSR1 (0.47) | NPSR1L3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL9164056 | 0.79 | NPSR1 (0.47) | NPSR1L3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL9488212 | 0.76 | L3MBTL1 (0.49) | NPSR1L3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL31599138 | 0.74 | SIGMAR1 (0.51) | NPSR1L3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL11500029 | 0.74 | SIGMAR1 (0.51) | NPSR1L3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL4459204 | 0.74 | NPSR1 (0.50) | NPSR1L3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL29661169 | 0.74 | NPSR1 (0.50) | NPSR1L3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL3994729 | 0.74 | L3MBTL1 (0.50) | NPSR1L3MBTL1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141096-A1 | SUBSTITUTED SPIRO-ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |
| US-6433228-B1 | REACTING AN ANILINE COMPOUND WITH AROMATIC DIAZONIUM COMPOUND, THEN ACRYLIC COMPOUND; CYCLIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-13 | — | — | US | disclosed |
| EP-1007498-B1 | PROCESS FOR PREPARING 2-HALOGENATED INDAN-1-ONES | BAYER AG (DE) | 2002-02-06 | — | — | EP | disclosed |
| EP-1007498-A1 | PROCESS FOR PREPARING 2-HALOGENATED INDAN-1-ONES | Bayer Aktiengesellschaft (DE) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999010306-A1 | PROCESS FOR PREPARING 2-HALOGENATED INDAN-1-ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-04 | — | — | WO | disclosed |