SCHEMBL4463331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4461986	0.83	TPSAB1 (0.48)	CACNA2D1CACNA1BCACNB1CACNA1CHTT
	SCHEMBL4462451	0.77	CACNA2D1 (0.53)	CACNA2D1CACNA1BCACNB1CACNA1CHTT
	SCHEMBL4457633	0.76	CACNA2D1 (0.45)	CACNA2D1CACNA1BCACNB1CACNA1CBIRC2
	SCHEMBL8282230	0.74	CACNA2D1 (0.44)	CACNA2D1CACNA1BCACNB1CACNA1CHTT
	SCHEMBL4557152	0.73	KCNA3 (0.43)	—
	SCHEMBL5634490	0.71	CACNA2D1 (0.52)	CACNA2D1CACNA1BCACNB1CACNA1CHTT
	SCHEMBL7714056	0.67	KDM4D (0.45)	—
	SCHEMBL7714059	0.67	KDM4D (0.45)	—
	SCHEMBL5543946	0.66	CACNA2D1 (0.54)	CACNA2D1CACNA1BCACNB1CACNA1C
	SCHEMBL22148074	0.65	SLC6A9 (0.42)	OPRM1OPRL1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.