Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463354 | 1.00 | FFAR1 (0.36) | FFAR1CCR5EPHX2P2RX7KMT2A | |
| SCHEMBL4463357 | 1.00 | FFAR1 (0.36) | FFAR1CCR5EPHX2P2RX7KMT2A | |
| SCHEMBL4463346 | 1.00 | FFAR1 (0.36) | FFAR1CCR5EPHX2P2RX7KMT2A | |
| SCHEMBL4463349 | 1.00 | FFAR1 (0.36) | FFAR1CCR5EPHX2P2RX7KMT2A | |
| SCHEMBL9046972 | 0.88 | ACKR3 (0.35) | CCR5P2RX7KMT2ACHRM1GRIN2B | |
| SCHEMBL9048300 | 0.87 | CCR5 (0.37) | FFAR1CCR5EPHX2 | |
| SCHEMBL9048288 | 0.87 | CCR5 (0.37) | FFAR1CCR5EPHX2 | |
| SCHEMBL9047586 | 0.87 | NPC1 (0.41) | CCR5KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9048290 | 0.87 | CCR5 (0.37) | FFAR1CCR5EPHX2 | |
| SCHEMBL9047592 | 0.87 | NPC1 (0.41) | CCR5KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-1931359-A4 | COMBINATION THERAPY FOR CONTROLLED CARBOHYDRATE DIGESTION | ELIXIR PHARMACEUTICALS INC (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1931359-A2 | COMBINATION THERAPY FOR CONTROLLED CARBOHYDRATE DIGESTION | Elixir Pharmaceuticals, Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007033292-A2 | COMBINATION THERAPY FOR CONTROLLED CARBOHYDRATE DIGESTION | ELIXIR PHARMACEUTICALS, INC. (US) | 2007-03-22 | — | — | WO | disclosed |
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |