Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 7/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048290 | 1.00 | CCR5 (0.37) | CCR5CNR2SLC6A1FFAR1EPHX2 | |
| SCHEMBL9048295 | 1.00 | CCR5 (0.37) | CCR5CNR2SLC6A1FFAR1EPHX2 | |
| SCHEMBL9048300 | 1.00 | CCR5 (0.37) | CCR5CNR2SLC6A1FFAR1EPHX2 | |
| SCHEMBL9048285 | 1.00 | CCR5 (0.37) | CCR5CNR2SLC6A1FFAR1EPHX2 | |
| SCHEMBL4463349 | 0.87 | FFAR1 (0.36) | CCR5FFAR1EPHX2 | |
| SCHEMBL4463342 | 0.87 | FFAR1 (0.36) | CCR5FFAR1EPHX2 | |
| SCHEMBL4463354 | 0.87 | FFAR1 (0.36) | CCR5FFAR1EPHX2 | |
| SCHEMBL4463346 | 0.87 | FFAR1 (0.36) | CCR5FFAR1EPHX2 | |
| SCHEMBL4463357 | 0.87 | FFAR1 (0.36) | CCR5FFAR1EPHX2 | |
| SCHEMBL9049255 | 0.85 | CCR5 (0.37) | CCR5CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |