Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.79 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.76 |
| ▸ | ABL1 | P00519 | 1/20 | 0.76 |
| ▸ | IKBKB | O14920 | 2/20 | 0.71 |
| ▸ | CHUK | O15111 | 2/20 | 0.71 |
| ▸ | IKBKG | Q9Y6K9 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | AKT1 | P31749 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | JUN | P05412 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194289 | 0.95 | SNCA (0.88) | SNCAGLO1ABL1IKBKBCHUK | |
| SCHEMBL3208332 | 0.84 | GLO1 (0.71) | SNCAGLO1ABL1IKBKBCHUK | |
| SCHEMBL3208354 | 0.84 | GLO1 (0.71) | SNCAGLO1ABL1IKBKBCHUK | |
| SCHEMBL3208339 | 0.84 | GLO1 (0.71) | SNCAGLO1ABL1IKBKBCHUK | |
| SCHEMBL7523992 | 0.84 | MAPT (1.00) | SNCAGLO1ABL1IKBKBCHUK | |
| SCHEMBL23817770 | 0.83 | GLO1 (1.00) | SNCAGLO1ABL1IKBKBCHUK | |
| SCHEMBL7585369 | 0.83 | GLO1 (0.87) | SNCAGLO1ABL1IKBKBCHUK | |
| SCHEMBL30497483 | 0.83 | GLO1 (0.87) | SNCAGLO1ABL1IKBKBCHUK | |
| SCHEMBL29449976 | 0.83 | GLO1 (1.00) | SNCAGLO1ABL1IKBKBCHUK | |
| SCHEMBL12394170 | 0.80 | MAPT (0.85) | SNCAGLO1ABL1IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507864-B2 | Method for the synthesis of curcumin analogues | SALISBURY UNIVERSITY (US) | 2009-03-24 | — | — | US | disclosed |
| US-20080033055-A1 | Method for the Synthesis of Curcumin Analogues | SALISBURY UNIVERSITY | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033055-A1 | Method for the Synthesis of Curcumin Analogues | APP, PSEN1, SQLE | SNCA 73/4885GLO1 341/4885ABL1 3795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.