Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 5/20 | 0.87 |
| ▸ | ABL1 | P00519 | 1/20 | 0.87 |
| ▸ | IKBKB | O14920 | 2/20 | 0.81 |
| ▸ | CHUK | O15111 | 2/20 | 0.81 |
| ▸ | IKBKG | Q9Y6K9 | 2/20 | 0.81 |
| ▸ | SNCA | P37840 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA3 | P07451 | 2/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | CA4 | P22748 | 2/20 | 0.68 |
| ▸ | CA6 | P23280 | 2/20 | 0.68 |
| ▸ | CA5A | P35218 | 2/20 | 0.68 |
| ▸ | CA7 | P43166 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.68 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497483 | 1.00 | GLO1 (0.87) | GLO1ABL1IKBKBCHUKIKBKG | |
| SCHEMBL29449976 | 0.89 | GLO1 (1.00) | GLO1ABL1IKBKBCHUKIKBKG | |
| SCHEMBL23817770 | 0.89 | GLO1 (1.00) | GLO1ABL1IKBKBCHUKIKBKG | |
| SCHEMBL7581752 | 0.89 | GLO1 (0.69) | GLO1ABL1IKBKBCHUKIKBKG | |
| SCHEMBL31110546 | 0.87 | GLO1 (0.67) | GLO1ABL1IKBKBCHUKIKBKG | |
| SCHEMBL2213640 | 0.87 | MAPT (0.77) | GLO1ABL1IKBKBCHUKIKBKG | |
| SCHEMBL728186 | 0.85 | GLO1 (0.83) | GLO1ABL1IKBKBCHUKIKBKG | |
| SCHEMBL7194289 | 0.83 | SNCA (0.88) | GLO1ABL1IKBKBCHUKIKBKG | |
| SCHEMBL4463365 | 0.83 | SNCA (0.79) | GLO1ABL1IKBKBCHUKIKBKG | |
| SCHEMBL12394170 | 0.83 | MAPT (0.85) | GLO1ABL1IKBKBCHUKIKBKG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263454-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | Praecis Pharmaceuticals Incorporated (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2000052048-A9 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARM INC (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-1161449-A1 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | Praecis Pharmaceuticals Incorporated (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2001058470-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2001-08-16 | — | — | WO | disclosed |
| WO-2000052048-A1 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2000-09-08 | — | — | WO | disclosed |