SCHEMBL4463680

SCHEMBL4463680

Cc1cc(-c2ccccc2)c(OP(=O)(O)O)c(-c2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 3/20 0.49
GPR84 Q9NQS5 1/20 0.45
HDAC7 Q8WUI4 1/20 0.44
INPPL1 O15357 4/20 0.43
INPP5A Q14642 3/20 0.43
INPP5B P32019 1/20 0.43
BACE1 P56817 2/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.42
AKT1 P31749 1/20 0.41
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
HPGD P15428 1/20 0.39
PDE3A Q14432 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38
PDE4D Q08499 1/20 0.38
THRA P10827 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28667492 0.88 SRC (0.50) SRCHDAC7INPPL1INPP5AINPP5B
SCHEMBL27780601 0.82 INPPL1 (0.53) SRCGPR84INPPL1INPP5AINPP5B
SCHEMBL5518516 0.80 PTGDR2 (0.57) SRCGPR84HDAC7INPPL1INPP5A
SCHEMBL10901422 0.78 INPPL1 (0.46) SRCGPR84INPPL1INPP5AINPP5B
SCHEMBL5512636 0.77 SRC (0.43) SRCGPR84INPPL1INPP5AINPP5B
SCHEMBL1681135 0.76 GPR84 (0.40) SRCGPR84HDAC7INPPL1INPP5A
SCHEMBL1426990 0.76 SRC (0.42) SRCGPR84INPPL1INPP5AINPP5B
SCHEMBL10708888 0.75 METAP2 (0.44) HDAC7BACE1PTGDR2ALDH1A1KDM4E
SCHEMBL10534592 0.75 INPPL1 (0.48) SRCGPR84INPPL1INPP5AINPP5B
SCHEMBL11062406 0.74 GPR84 (0.44) SRCGPR84INPPL1INPP5AINPP5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118591592-A Aromatic polycarbonate resin composition and molded article thereof 帝人株式会社 2024-09-03 CN disclosed
EP-3732247-B1 A POLYCARBONATE COMPOSITION AND A MOLDED ARTICLE PREPARED FROM THE SAME COVESTRO DEUTSCHLAND AG (DE) 2022-09-28 EP disclosed
CN-113195078-A Membrane with reinforced potting material 纳诺斯通沃特公司 2021-07-30 CN disclosed
US-20200392330-A1 A POLYCARBONATE COMPOSITION AND A MOLDED ARTICLE PREPARED FROM THE SAME COVESTRO DEUTSCHLAND AG (DE) 2020-12-17 US disclosed
EP-3732247-A1 A POLYCARBONATE COMPOSITION AND A MOLDED ARTICLE PREPARED FROM THE SAME Covestro Deutschland AG (DE) 2020-11-04 EP disclosed
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed