⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456930 | 1.00 | — | — | |
| SCHEMBL360993 | 0.83 | KDM4E (0.41) | — | |
| SCHEMBL7967193 | 0.83 | KDM4E (0.41) | — | |
| SCHEMBL8948968 | 0.82 | — | — | |
| SCHEMBL6743812 | 0.81 | KDM4E (0.48) | — | |
| SCHEMBL6743815 | 0.81 | KDM4E (0.48) | — | |
| SCHEMBL13665338 | 0.77 | — | — | |
| SCHEMBL2537106 | 0.77 | — | — | |
| SCHEMBL452905 | 0.77 | — | — | |
| SCHEMBL711331 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002536440-A | — | — | 2002-10-29 | — | — | JP | claimed |
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | claimed |
| WO-2023088426-A1 | OXOBUTAN(-2-ENOIC ACID) ACID COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF, AND HERBICIDE | 南开大学 | 2023-05-25 | — | — | WO | disclosed |
| US-20160214973-A1 | STORE OVERLOAD-INDUCED CALCIUM RELEASE INHIBITORS AND METHODS FOR PRODUCING AND USING THE SAME | UTI LIMITED PARTNERSHIP (CA) | 2016-07-28 | — | — | US | disclosed |
| US-7608727-B2 | Process for the preparation of furan compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-10-27 | — | — | US | disclosed |
| EP-1826202-A1 | Process for the preparation of furan compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-08-29 | — | — | EP | disclosed |
| US-20070197806-A1 | Process for the preparation of furan compounds | DAICEL CHEMICAL INDUSTRIES, LTD. | 2007-08-23 | — | — | US | disclosed |
| US-6900273-B1 | Low-hygroscopicity low-birefringence resin compositions, molding material obtained therefrom, sheet or film, and optical part | HITACHI CHEMICAL CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| EP-1465885-A4 | NOVEL ALKYL/ARYL HYDROXY OR KETO THIEPINE COMPOUNDS AS INHIBITORS OF APICAL SODIUM CO-DEPENDENT BILE ACID TRANSPORT (ASBT) AND TAUROCHOLATE UPTAKE | PHARMACIA CORP (US) | 2005-04-27 | — | — | EP | disclosed |
| US-6852753-B2 | Alkyl/aryl hydroxy or keto thiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake | PHARMACIA CORPORATION (US) | 2005-02-08 | — | — | US | disclosed |
| US-20030195218-A1 | Novel alkyl/aryl hydroxy or keto thiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake | PHARMACIA CORPORATION | 2003-10-16 | — | — | US | disclosed |
| WO-2003061604-A2 | NOVEL ALKYL/ARYL HYDROXY OR KETO THIEPINES. | PHARMACIA CORPORATION (US) | 2003-07-31 | — | — | WO | disclosed |
| WO-2003040127-A1 | NOVEL MONO- AND DI-FLUORINATED BENZOTHIEPINE COMPOUNDS AS INHIBITORS OF APICAL SODIUM CO-DEPENDENT BILE ACID TRANSPORT (ASBT) AND TAUROCHOLATE UPTAKE | G.D. SEARLE LLC (US) | 2003-05-15 | — | — | WO | disclosed |
| EP-1205517-A1 | LOW-HYGROSCOPICITY LOW-BIREFRINGENCE RESIN COMPOSITIONS, MOLDING MATERIAL OBTAINED THEREFROM, SHEET OR FILM, AND OPTICAL PART | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-0711813-B1 | Antifouling coating composition | HITACHI CHEMICAL CO LTD (JP) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | disclosed |
| US-5773508-A | BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0711813-A2 | Coating varnish composition and antifouling coating composition | Hitachi Chemical Co., Ltd. (JP) | 1996-05-15 | — | — | EP | disclosed |