⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27651269 | 0.98 | KDM4E (0.42) | — | |
| Benzene SCHEMBL28297131 | 0.98 | KDM4E (0.42) | — | |
| SCHEMBL6743812 | 0.81 | KDM4E (0.48) | — | |
| SCHEMBL6743815 | 0.81 | KDM4E (0.48) | — | |
| SCHEMBL8948968 | 0.77 | — | — | |
| SCHEMBL4464036 | 0.77 | — | — | |
| SCHEMBL13665338 | 0.77 | — | — | |
| SCHEMBL452905 | 0.77 | — | — | |
| SCHEMBL31456930 | 0.77 | — | — | |
| SCHEMBL2537106 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 534 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2636669-B1 | PYRAZOLE AMIDE COMPOUND AND USE THEREOF AS FUNGICIDE | SINOCHEM CORP (CN) | 2015-10-21 | — | — | EP | claimed |
| CN-104177340-A | Novel quinazoline (sulfur) ketone compound and application | SINOCHEM CORP | 2014-12-03 | — | — | CN | claimed |
| US-8614214-B2 | Pyrazole amide compounds and uses thereof | SINOCHEM CORPORATION (CN) | 2013-12-24 | — | — | US | claimed |
| EP-2636669-A1 | PYRAZOLE AMIDE COMPOUND AND USE THEREOF | Sinochem Corporation (CN) | 2013-09-11 | — | — | EP | claimed |
| US-20130225585-A1 | PYRAZOLE AMIDE COMPOUNDS AND USES THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2013-08-29 | — | — | US | claimed |
| EP-0578137-B1 | Microbiological process for the production of 5-hydroxy-2-pyrazine carboxylic acid | LONZA AG (CH) | 1996-10-16 | — | — | EP | claimed |
| US-20240229037-A1 | SIRNA TARGETING 17Beta-HYDROXYSTEROID DEHYDROGENASE TYPE 13 AND SIRNA CONJUGATE | TUOJIE BIOTECH (SHANGHAI) CO., LTD. (CN) | 2024-07-11 | — | — | US | disclosed |
| CN-118265786-A | Microtubule-associated protein Tau (MAPT) iRNA pharmaceutical compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2024-06-28 | — | — | CN | disclosed |
| US-20240209373-A1 | ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 1 (ELOVL1) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| US-20240200077-A1 | STEAROYL-COA DESATURASE 5 (SCD5) IRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-06-20 | — | — | US | disclosed |
| EP-3784269-B1 | INTEGRIN TARGETING LIGANDS AND USES THEREOF | ARROWHEAD PHARMACEUTICALS INC (US) | 2024-06-05 | — | — | EP | disclosed |
| EP-4376953-A1 | PEPTIDE LIGANDS FOR CNS AND OCULAR DELIVERY OF RNAI COMPOUNDS | Alnylam Pharmaceuticals, Inc. (US) | 2024-06-05 | — | — | EP | disclosed |
| CN-118076738-A | LPA-targeting siRNA and conjugates | 上海拓界生物医药科技有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-5336593-A | With pyrazolotriazole magenta couplers, for image durability, lightfastness, efficient color formation, color reproduction | KONICA CORPORATION (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0600450-A1 | A Silver halide color photographic light-sensitive material and a method for forming a color image by using the same | KONICA CORPORATION (JP) | 1994-06-08 | — | — | EP | disclosed |
| US-5314796-A | Silver halide color photographic light sensitive material | KONICA CORPORATION (JP) | 1994-05-24 | — | — | US | disclosed |
| EP-0568196-A1 | Light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1993-11-03 | — | — | EP | disclosed |
| EP-0563910-A1 | Silver halide color photographic light sensitive material | KONICA CORPORATION (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-4609734-A | Process for the production of 2-hydroxypyridines from 2-pyridine carboxylic acid-N-oxides | LONZA LTD. (CH) | 1986-09-02 | — | — | US | disclosed |
| US-4556716-A | HALOGENATION OF THE 2-CARBOXYLPYRIDINE OXIDE | LONZA LTD. (CH) | 1985-12-03 | — | — | US | disclosed |