⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202926 | 0.83 | KDM4E (0.41) | — | |
| SCHEMBL15602609 | 0.82 | KDM4E (0.37) | — | |
| SCHEMBL6743812 | 0.81 | KDM4E (0.48) | — | |
| SCHEMBL6743815 | 0.81 | KDM4E (0.48) | — | |
| SCHEMBL4464036 | 0.77 | — | — | |
| SCHEMBL31456930 | 0.77 | — | — | |
| SCHEMBL8948968 | 0.77 | — | — | |
| SCHEMBL711331 | 0.77 | — | — | |
| SCHEMBL13665338 | 0.77 | — | — | |
| SCHEMBL2537106 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040969-B2 | Compounds I | Benevolentai Cambridge Limited (GB) | 2021-06-22 | — | — | US | claimed |
| US-9493457-B2 | 4,5,6,7-tetrahyroimidazo[4,5-c]pyridine compounds | PROXIMAGEN LIMITED (GB) | 2016-11-15 | — | — | US | claimed |
| US-20150218161-A1 | NEW COMPOUNDS I | PROXIMAGEN, LLC | 2015-08-06 | — | — | US | claimed |
| US-9035066-B2 | Method of using 4,5,6,7-tetrahydroimidazo[4,5-C]pyridine compounds | PROXIMAGEN LIMITED (GB) | 2015-05-19 | — | — | US | claimed |
| US-20140121219-A1 | New Compounds I | PROXIMAGEN LIMITED (GB) | 2014-05-01 | — | — | US | claimed |
| US-8324257-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-12-04 | — | — | US | claimed |
| US-20100041719-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2010-02-18 | — | — | US | claimed |
| EP-2081918-A2 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | Array Biopharma, Inc. (US) | 2009-07-29 | — | — | EP | claimed |
| WO-2008042928-A2 | OXADIAZOLE AND THIADIAZOLE DERIVATIVES AS MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA, INC. (US) | 2008-04-10 | — | — | WO | claimed |
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2024-06-06 | — | — | US | disclosed |
| EP-4143167-B1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2024-05-15 | — | — | EP | disclosed |
| WO-2024061768-A1 | AZOLE PESTICIDAL COMPOUNDS | BASF SE (DE) | 2024-03-28 | — | — | WO | disclosed |
| US-11931347-B2 | Method of screening for agents for differentiating stem cells | MINERVA BIOTECHNOLOGIES CORPORATION (US) | 2024-03-19 | — | — | US | disclosed |
| WO-2024028243-A1 | PYRAZOLO PESTICIDAL COMPOUNDS | BASF SE (DE) | 2024-02-08 | — | — | WO | disclosed |
| EP-0936216-A1 | NOVEL ACETAMIDE DERIVATIVES AND PROTEASE INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-08-18 | — | — | EP | disclosed |
| WO-1997006153-A1 | 4-ALKYL-1,3-OXA(THIA)ZOLINE DERIVATIVES, THEIR PREPARATION AND USE FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-20 | — | — | WO | disclosed |
| US-5569665-A | Peptidyl derivatives and their use as metalloproteinases inhibitors | CELLTECH LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |
| EP-0605682-A1 | PEPTIDYL DERIVATIVES AND THEIR USE AS METALLOPROTEINASES INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993024449-A1 | PEPTIDYL DERIVATIVES AND THEIR USE AS METALLOPROTEINASES INHIBITORS | CELLTECH LIMITED (GB) | 1993-12-09 | — | — | WO | disclosed |
| US-4264498-A | REACTED WITH AN ACID, ITS ACID HALIDE, OR ANHYDRIDE IN THE PRESENCE OF BORON TRIHALIDE AND AN ORGANIC BASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |