SCHEMBL4464058

SCHEMBL4464058

CCCCOCn1cccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
CYP3A4 P08684 1/20 0.34
ALDH1A1 P00352 3/20 0.34
APAF1 O14727 2/20 0.34
RAD52 P43351 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 2/20 0.33
CYP19A1 P11511 2/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
LTA4H P09960 1/20 0.32
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2360217 0.86 HSD17B10 (0.31)
SCHEMBL12376948 0.78 TSHR (0.41) TSHRCYP3A4ALDH1A1RAD52NPSR1
SCHEMBL31065557 0.74 TP53 (0.33)
SCHEMBL21402319 0.74 TBXAS1 (0.55) CYP3A4ALDH1A1CYP19A1CYP1A2CYP2C9
SCHEMBL16731564 0.72 APAF1 (0.54) TSHRCYP3A4ALDH1A1APAF1RAD52
Benzene SCHEMBL1450969 0.72 TSHR (0.60) TSHRCYP3A4ALDH1A1SMN1; SMN2HPGD
SCHEMBL20527604 0.71 MEN1 (0.38) ALDH1A1APAF1RAD52NPSR1SMN1; SMN2
SCHEMBL8600029 0.68 TSHR (0.71) TSHRCYP3A4ALDH1A1SMN1; SMN2HPGD
SCHEMBL15167 0.68
SCHEMBL439119 0.68 TSHR (0.71) TSHRCYP3A4ALDH1A1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7576161-B2 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers CHEVRON ORONITE COMPANY LLC (US) 2009-08-18 US claimed
US-20050282972-A1 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers STOKES CASEY D 2005-12-22 US claimed
EP-1489109-B1 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation CHEVRON ORONITE CO (US) 2015-08-19 EP disclosed
US-7576161-B2 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers CHEVRON ORONITE COMPANY LLC (US) 2009-08-18 US disclosed
US-20050282972-A1 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers STOKES CASEY D 2005-12-22 US disclosed
US-6969744-B2 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2005-11-29 US disclosed
US-20040260033-A1 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation UNIVERSITY OF SOUTHERN MISSISSIPPI 2004-12-23 US disclosed
EP-1489109-A2 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation Chevron Oronite Company LLC (US) 2004-12-22 EP disclosed