Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97873 | 0.95 | CES2 (0.38) | CES1CES2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30205678 | 0.93 | CES2 (0.39) | CES1CES2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30205801 | 0.93 | CES2 (0.39) | CES1CES2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30205669 | 0.93 | CES2 (0.39) | CES1CES2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL97173 | 0.93 | CES2 (0.39) | CES1CES2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL98404 | 0.93 | CES2 (0.39) | CES1CES2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30205672 | 0.93 | CES2 (0.39) | CES1CES2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL97467 | 0.93 | CES2 (0.39) | CES1CES2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4454855 | 0.91 | CES1 (0.34) | CES1CES2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL3689569 | 0.91 | ALDH1A1 (0.31) | CES1CES2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680469-B1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2009-01-07 | — | — | EP | claimed |