Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 4/20 | 0.33 |
| ▸ | FPR2 | P25090 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368786 | 1.00 | CPB2 (0.39) | CPB2DGAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3368795 | 1.00 | CPB2 (0.39) | CPB2DGAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3368783 | 1.00 | CPB2 (0.39) | CPB2DGAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4464180 | 1.00 | CPB2 (0.39) | CPB2DGAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3367087 | 0.86 | DGAT1 (0.38) | CPB2DGAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3367084 | 0.86 | DGAT1 (0.38) | CPB2DGAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3367092 | 0.86 | DGAT1 (0.38) | CPB2DGAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3369093 | 0.83 | USP30 (0.41) | CPB2DGAT1BCL2POLBFPR3 | |
| SCHEMBL3369092 | 0.83 | USP30 (0.41) | CPB2DGAT1BCL2POLBFPR3 | |
| SCHEMBL3369097 | 0.83 | USP30 (0.41) | CPB2DGAT1BCL2POLBFPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582659-B2 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof | MERCK & CO., INC. (US) | 2009-09-01 | — | — | US | disclosed |