Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459926 | 0.81 | KIF11 (0.54) | ITGB1ITGA4RAB9ANPC1 | |
| SCHEMBL4454786 | 0.81 | ITGB1 (0.54) | ITGB1ITGA4RAB9ANPC1CDK5 | |
| Hydrochloric Acid SCHEMBL4455280 | 0.80 | ITGB1 (0.53) | ITGB1ITGA4RAB9ANPC1CDK5 | |
| SCHEMBL12793317 | 0.78 | ITGB1 (0.48) | ITGB1ITGA4RAB9ANPC1CDK5 | |
| SCHEMBL4460025 | 0.77 | ITGB1 (0.50) | ITGB1ITGA4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4456198 | 0.77 | ITGB1 (0.50) | ITGB1ITGA4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6362419 | 0.73 | GAA (0.52) | ITGB1ITGA4RAB9ANPC1CDK5 | |
| SCHEMBL12848183 | 0.72 | ITGB1 (0.43) | ITGB1ITGA4ALDH1A1MAPT | |
| SCHEMBL12847996 | 0.72 | ITGB1 (0.43) | ITGB1ITGA4ALDH1A1MAPT | |
| SCHEMBL3430939 | 0.72 | MAPT (0.54) | ITGB1ITGA4ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |