SCHEMBL446451

SCHEMBL446451

CCC(CC(=O)O)C(O)O

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.42
GPR84 Q9NQS5 4/20 0.40
MAPT P10636 1/20 0.39
GABRR1 P24046 2/20 0.39
LMNA P02545 1/20 0.39
FFAR3 O14843 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
CACNB3 P54284 1/20 0.32
CACNA2D1 P54289 1/20 0.32
CACNA1C Q13936 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5077882 0.86 SLC22A6 (0.45) SLC22A6SMN1; SMN2GPR84MAPTGABRR1
SCHEMBL678102 0.86 SLC22A6 (0.45) SLC22A6SMN1; SMN2GPR84MAPTGABRR1
SCHEMBL27753421 0.83 SLC22A6 (0.43) SLC22A6SMN1; SMN2GPR84MAPTGABRR1
SCHEMBL27945267 0.83 SLC22A6 (0.43) SLC22A6SMN1; SMN2GPR84MAPTGABRR1
SCHEMBL5078846 0.82 SLC22A6 (0.43) SLC22A6SMN1; SMN2GPR84MAPTGABRR1
SCHEMBL9059911 0.80 SLC22A6 (0.42) SLC22A6SMN1; SMN2GPR84MAPTGABRR1
SCHEMBL1572826 0.79 SMN1; SMN2 (0.42) SLC22A6SMN1; SMN2GPR84MAPTGABRR1
SCHEMBL2510902 0.79 SLC22A6 (0.46) SLC22A6SMN1; SMN2GPR84MAPTGABRR1
SCHEMBL28606217 0.78 LMNA (0.41) SLC22A6SMN1; SMN2GPR84MAPTGABRR1
SCHEMBL18222806 0.77 MME (0.39) SLC22A6SMN1; SMN2GPR84FFAR3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114686092-A Photocureable coating capable of being used for metal protection and preparation method thereof 中海油常州涂料化工研究院有限公司 2022-07-01 CN claimed
US-9580705-B2 DHAD variants and methods of screening BUTAMAX ADVANCED BIOFUELS LLC (US) 2017-02-28 US claimed
WO-2014151190-A1 DHAD VARIANTS AND METHODS OF SCREENING BUTAMAX ADVANCED BIOFUELS LLC (US) 2014-09-25 WO claimed
US-20140273116-A1 DHAD VARIANTS AND METHODS OF SCREENING BUTAMAX ADVANCED BIOFUELS LLC (US) 2014-09-18 US claimed
US-20140186910-A1 DHAD Variants for Butanol Production BUTAMAXTM ADVANCED BIOFUELS LLC (US) 2014-07-03 US claimed
WO-2014106107-A2 DHAD VARIANTS FOR BUTANOL PRODUCTION BUTAMAX (TM) ADVANCED BIOFUELS LLC (US) 2014-07-03 WO claimed
CN-114686092-A Photocureable coating capable of being used for metal protection and preparation method thereof 中海油常州涂料化工研究院有限公司 2022-07-01 CN disclosed
US-10308964-B2 Activity of Fe—S cluster requiring proteins BUTAMAX ADVANCED BIOFUELS LLC (US) 2019-06-04 US disclosed
US-10287566-B2 DHAD variants and methods of screening BUTAMAX ADVANCED BIOFUELS LLC (US) 2019-05-14 US disclosed
CN-108452311-A Composition for enhancing energetic supersession and method 纽斯尔特科学公司 2018-08-28 CN disclosed
CN-108295058-A Composition for enhancing energetic supersession and method 纽斯尔特科学公司 2018-07-20 CN disclosed
CN-108261547-A For adjusting the composition of metabolic pathway and method 纽斯尔特科学公司 2018-07-10 CN disclosed
EP-2536821-B1 IMPROVING ACTIVITY OF FE-S CLUSTER REQUIRING PROTEINS BUTAMAX TM ADVANCED BIOFUELS (US) 2018-06-13 EP disclosed
WO-2010037119-A1 ENHANCED IRON-SULFUR CLUSTER FORMATION FOR INCREASED DIHYDROXY-ACID DEHYDRATASE ACTIVITY IN LACTIC ACID BACTERIA Butamax™ Advanced Biofuels LLC (US) 2010-04-01 WO disclosed
US-20100081154-A1 IDENTIFICATION AND USE OF BACTERIAL [2Fe-2S] DIHYDROXY-ACID DEHYDRATASES BUTAMAX(TM) ADVANCED BIOFUELS LLC (US) 2010-04-01 US disclosed
US-20100081154-A1 IDENTIFICATION AND USE OF BACTERIAL [2Fe-2S] DIHYDROXY-ACID DEHYDRATASES BUTAMAX(TM) ADVANCED BIOFUELS LLC (US) 2010-04-01 US disclosed
WO-2010037105-A1 ENHANCED DIHYDROXY-ACID DEHYDRATASE ACTIVITY IN LACTIC ACID BACTERIA Butamax™ Advanced Biofuels LLC (US) 2010-04-01 WO disclosed
US-20100081182-A1 ENHANCED IRON-SULFUR CLUSTER FORMATION FOR INCREASED DIHYDROXY-ACID DEHYDRATASE ACTIVITY IN LACTIC ACID BACTERIA BUTAMAX(TM) ADVANCED BIOFUELS LLC (US) 2010-04-01 US disclosed
CN-101679985-A Mutant ILV5 gene and use thereof SUNTORY CO LTD 2010-03-24 CN disclosed
CN-1256313-A Method for the fermentative production of D-pantothenic acid using coryneform bacteria DEGUSSA (DE) 2000-06-14 CN disclosed