Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16356135 | 0.81 | MAPT (0.50) | HSD17B10ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL1186297 | 0.80 | HSD17B10 (0.59) | HSD17B10ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL1244430 | 0.80 | HSD17B10 (0.59) | HSD17B10ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL1186568 | 0.80 | HSD17B10 (0.59) | HSD17B10ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL9727031 | 0.78 | TDP1 (0.58) | HSD17B10ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL9727033 | 0.78 | TDP1 (0.58) | HSD17B10ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL28428178 | 0.76 | MEN1 (0.46) | HSD17B10ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL25336459 | 0.75 | MMP9 (0.66) | HSD17B10ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL249524 | 0.75 | HSD17B10 (0.63) | HSD17B10ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL8715641 | 0.75 | HSD17B10 (0.75) | HSD17B10ALDH1A1KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146696-A1 | USE OF INDOLE-3-CARBOXYLIC ESTERS FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE | Universität Tübingen (DE) | 2009-12-10 | — | — | WO | disclosed |