Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | CASR | P41180 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2672977 | 1.00 | HSD17B10 (0.63) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL247742 | 1.00 | HSD17B10 (0.63) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9718520 | 0.98 | HSD17B10 (0.61) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL4459970 | 0.98 | HSD17B10 (0.61) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| Chloromethane SCHEMBL29855624 | 0.96 | HSD17B10 (0.59) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28210163 | 0.94 | HSD17B10 (0.58) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28305666 | 0.92 | HSD17B10 (0.56) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| Alcohol SCHEMBL28032632 | 0.92 | MEN1 (0.64) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17571990 | 0.88 | ALDH1A1 (0.61) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28306863 | 0.87 | HSD17B10 (0.51) | HSD17B10MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240484-A1 | PYRIDAZINONE DERIVATIVES AS THYROID RECEPTOR AGONISTS AND USES THEREOF | Aligos Therapeutics, Inc. (US) | 2023-09-13 | — | — | EP | claimed |
| WO-2022099049-A1 | PYRIDAZINONE DERIVATIVES AS THYROID RECEPTOR AGONISTS AND USES THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | claimed |
| EP-2903979-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES | INHIBIKASE THERAPEUTICS INC (US) | 2020-08-19 | — | — | EP | claimed |
| EP-3364940-B1 | METHOD OF CHROMATOGRAPHIC SEPARATION | PROCTER & GAMBLE (US) | 2019-08-07 | — | — | EP | claimed |
| CN-108697719-A | Modulators of extracellular 5' -nucleotidase and uses thereof | 艾库斯生物科学有限公司 | 2018-10-23 | — | — | CN | claimed |
| CN-108558926-A | Organoaminodisilane precursors and methods of thin film deposition comprising the same | 弗萨姆材料美国有限责任公司 | 2018-09-21 | — | — | CN | claimed |
| US-10035759-B2 | Method of chromatographic separation | THE PROCTER & GAMBLE COMPANY (US) | 2018-07-31 | — | — | US | claimed |
| CN-103450242-B | Organoaminodisilane precursors and methods of thin film deposition comprising the same | 弗萨姆材料美国有限责任公司 | 2018-05-01 | — | — | CN | claimed |
| US-20170036994-A1 | METHOD OF CHROMATOGRAPHIC SEPARATION | THE PROCTER & GAMBLE COMPANY | 2017-02-09 | — | — | US | claimed |
| CN-105801612-A | Organoaminodisilane precursors and methods for depositing films comprising same | 气体产品与化学公司 | 2016-07-27 | — | — | CN | claimed |
| WO-2004006925-A1 | N-SULFONYLPIPERIDINES AS METALLOPROTEINASE INHIBITORS (TACE) | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | claimed |
| US-RE37303-E1 | Imidazole compounds and their therapeutic applications | INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2001-07-31 | — | — | US | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | claimed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | claimed |
| US-5514818-A | POLYSACCHARIDE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-07 | — | — | US | claimed |
| EP-0253372-B1 | 1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indoles, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1994-09-28 | — | — | EP | claimed |
| US-5081117-A | Treatment of memory dysfunctions such as in Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-14 | — | — | US | claimed |
| EP-0085204-B1 | PROCESS FOR THE CO-PRODUCTION OF CARBOXYLIC ACIDS AND CARBOXYLIC ACID ESTERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-02-12 | — | — | EP | claimed |
| EP-0031385-A1 | PROCESS FOR PREPARING POLYMETHYLENEPOLYPHENYL POLYCARBAMATE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1981-07-08 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170036994-A1 | METHOD OF CHROMATOGRAPHIC SEPARATION | AVPR2, SHBG, AVPR1B | HSD17B10 336/4885MEN1 1199/4885KMT2A 4552/4885 |
| US-10035759-B2 | Method of chromatographic separation | AVPR2, SHBG, AVPR1B | HSD17B10 336/4885MEN1 1199/4885KMT2A 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.