Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 14/20 | 0.60 |
| ▸ | PGR | P06401 | 9/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3649037 | 0.92 | NR3C1 (0.50) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4555162 | 0.91 | NR3C1 (0.56) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4044134 | 0.91 | NR3C1 (0.62) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3657196 | 0.83 | NR3C1 (0.52) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL6669693 | 0.82 | NR3C1 (0.64) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3652210 | 0.81 | NR3C1 (0.41) | NR3C1NR3C2PGR | |
| SCHEMBL3658109 | 0.81 | NR3C1 (0.46) | NR3C1NR3C2PGR | |
| SCHEMBL4447862 | 0.80 | NR3C1 (0.71) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3650787 | 0.80 | NR3C1 (0.64) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3657603 | 0.79 | NR3C1 (0.46) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170175-A1 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, OR AMELIORATING INFLAMMATORY PAIN | BAUSCH & LOMB INCORPORATED (US) | 2012-12-13 | — | — | WO | disclosed |
| EP-2051736-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST AND AN IMMUNOSUPPRESSIVE AGENT FOR TREATING DRY EYE | Bausch & Lomb Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008005686-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST AND AN IMMUNOSUPPRESSIVE AGENT FOR TREATING DRY EYE | BAUSCH & LOMB INCORPORATED (US) | 2008-01-10 | — | — | WO | disclosed |
| EP-1490062-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003082280-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-10-09 | — | — | WO | disclosed |