Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.64 |
| ▸ | PGR | P06401 | 8/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685155 | 0.89 | NR3C1 (0.63) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4447862 | 0.89 | NR3C1 (0.71) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4555162 | 0.87 | NR3C1 (0.56) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3650787 | 0.87 | NR3C1 (0.64) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4555971 | 0.86 | NR3C1 (0.64) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4555711 | 0.85 | NR3C1 (0.54) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4044134 | 0.84 | NR3C1 (0.62) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4552144 | 0.84 | NR3C1 (0.44) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3748995 | 0.83 | NR3C1 (0.69) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3752990 | 0.82 | NR3C1 (0.49) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490062-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003082280-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-10-09 | — | — | WO | disclosed |