Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464866 | 0.95 | TSHR (0.42) | SMN1; SMN2TSHRALDH1A1ALOX15CHRM2 | |
| SCHEMBL10711004 | 0.95 | TSHR (0.42) | SMN1; SMN2TSHRALDH1A1ALOX15CHRM2 | |
| SCHEMBL15196486 | 0.95 | TSHR (0.42) | SMN1; SMN2TSHRALDH1A1ALOX15CHRM2 | |
| Acetone SCHEMBL15323054 | 0.87 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRALDH1A1ALOX15CHRM2 | |
| SCHEMBL18668942 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRPPARAALOX15 | |
| SCHEMBL18668796 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRPPARASLC18A3ALOX15 | |
| SCHEMBL18668881 | 0.79 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHRALDH1A1SLC18A3 | |
| SCHEMBL12314325 | 0.78 | TSHR (0.43) | SMN1; SMN2TSHRALDH1A1ALOX15CHRM2 | |
| SCHEMBL12314349 | 0.78 | TSHR (0.43) | SMN1; SMN2TSHRALDH1A1ALOX15CHRM2 | |
| SCHEMBL3047899 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2PPARGPPARAKLK7CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214881-A1 | Propylene polymer catalyst donor component | INEOS USA LLC | 2008-09-04 | — | — | US | claimed |
| US-20080194782-A1 | Propylene polymer catalyst donor component | INEOS USA LLC | 2008-08-14 | — | — | US | claimed |
| US-7674943-B2 | Solid, hydrocarbon-insoluble, catalyst component containing magnesium, titanium, and halogen, and further contains an internal electron donor which does not contain a phthalate derivative, for example, ethyl (phenylacetoxy)acetate; stereospecific polymerization; highly crystalline propylene polymers | INEOS USA LLC (US) | 2010-03-09 | — | — | US | disclosed |
| US-20080214881-A1 | Propylene polymer catalyst donor component | INEOS USA LLC | 2008-09-04 | — | — | US | disclosed |
| US-20080194782-A1 | Propylene polymer catalyst donor component | INEOS USA LLC | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214881-A1 | Propylene polymer catalyst donor component | RAD52, NR2C2, PGR | SMN1; SMN2 2925/4885TSHR 294/4885PPARG 2045/4885 |
| US-20080194782-A1 | Propylene polymer catalyst donor component | RAD52, NR2C2, PGR | SMN1; SMN2 2925/4885TSHR 294/4885PPARG 2045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.