Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459326 | 0.85 | RAPGEF4 (0.31) | RAPGEF4 | |
| SCHEMBL10055035 | 0.68 | HPGD (0.67) | HPGDMAPTMEN1KMT2ANOS1 | |
| SCHEMBL6229701 | 0.67 | HPGD (0.65) | HPGDMAPTMEN1KMT2ANOS1 | |
| SCHEMBL146544 | 0.66 | MEN1 (0.50) | HPGDMAPTMEN1KMT2ANOS1 | |
| SCHEMBL11015099 | 0.65 | HPGD (0.63) | HPGDMAPTMEN1KMT2ANOS1 | |
| SCHEMBL20219041 | 0.65 | MAPT (0.48) | HPGDMAPTMEN1KMT2ANOS1 | |
| Hydrochloric Acid SCHEMBL5728329 | 0.65 | HPGD (0.49) | HPGDMAPTMEN1KMT2ANOS1 | |
| SCHEMBL6235610 | 0.65 | MAPT (0.50) | HPGDMAPTMEN1KMT2ANOS1 | |
| Hydrochloric Acid SCHEMBL27774106 | 0.64 | HPGD (0.61) | HPGDMAPTMEN1KMT2ANOS1 | |
| SCHEMBL30093210 | 0.64 | KMT2A (0.58) | HPGDMAPTMEN1KMT2ANOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601870-B2 | Such as Hexanoic acid (4-bromo-2,6-dimethyl-phenyl)-amide; potassium channel modulators; epilepsy | H. LUNDBECK A/S (DK) | 2009-10-13 | — | — | US | disclosed |